Comparing effects of carotid artery procedures on brain function and blood flow

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the long-term effects of carotid artery revascularization procedures, specifically carotid endarterectomy (CEA) and carotid artery stenting (CAS), on hemodynamics and cognitive function in patients with significant carotid artery stenosis. The researchers will analyze how changes in blood flow and arterial structure post-surgery relate to cognitive outcomes and the risk of complications such as restenosis. By combining clinical data with advanced imaging and computational modeling, the study seeks to establish new prognostic factors for patient outcomes following these interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Informed consent signed Patients with \>=70% symptomatic or \>=80% asymptomatic internal carotid stenosis

Exclusion Criteria:

Incapability to give informed consent Previous disabling stroke Contralateral carotid occlusion or \>70% stenosis Systemic disease judged non compatible with the procedures or randomization Suspected or manifested pregnancy General contraindications to MRI or CT studies

Where it's running

• Beijing Friendship Hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Mingyuan Liu, PhD
• Email: dr.mingyuanliu@pku.edu.cn
• Phone: +8613011157272

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating a new system for protecting the brain during carotid artery procedures

  This study is testing a new device to see if it can help protect the brain during carotid artery procedures for people with narrowed arteries.

  Recruiting Shenzhen Wecan Medical Technology Co.,Ltd · Beijing · NCT06959628

• Trans-carotid artery occlusion shunt for carotid revascularization

  Researchers will test a trans-carotid artery occlusion shunt used during endovascular revascularization in adults with symptomatic or high‑grade asymptomatic carotid artery stenosis.

  Recruiting Shenzhen Wecan Medical Technology Co.,Ltd · Beijing · NCT06924593

• Portable EEG to triage suspected stroke patients in ambulances

  This trial will test whether a portable dry‑electrode EEG headset (StrokePointer) can detect large vessel occlusion strokes in adults with suspected acute stroke so ambulance crews can take them directly to hospitals that perform thrombectomy.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam, North Holland · NCT06871969

• Remote ischemic conditioning after aneurysm clipping for ruptured brain aneurysms

  This test tries brief cycles of limb cuff inflation (remote ischemic conditioning) to see if it is safe and helps recovery in adults after surgical clipping of a ruptured brain aneurysm (aneurysmal subarachnoid hemorrhage).

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06819657

• Using deep brain stimulation to improve speech and arm function after stroke

  This study is testing if deep brain stimulation can help improve hand movement and speech in people who have had a stroke.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT06303869

• Predicting cerebral hyperperfusion syndrome after carotid artery procedures using deep learning

  This study is testing if deep learning can help predict which patients are at risk of developing cerebral hyperperfusion syndrome after carotid artery procedures.

  Recruiting State Institution "Republican Scientific and Practical Center" Cardiology, Belarus · Minsk · NCT05800821

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.