Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing early and late tracheostomy in patients with Guillain-Barre syndrome

Official title: Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome: Comparison of Clinical Outcomes- a Retrospective Study

Run by Meir Medical Center · NCT06612242 · Data updated 2026-11-12

This study is testing if doing a tracheostomy sooner rather than later can help patients with Guillain-Barre syndrome who need breathing support recover faster and have better outcomes.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorMeir Medical Center
Academic / other
Locations1 site (Kfar Saba)
StatusRecruiting
StartedFebruary 1, 2025
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedOctober 7, 2026
Trial IDNCT06612242 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-99 diagnosed with Guillain-Barre syndrome who are admitted to the ICU and require mechanical ventilation.

Probably not a fit

Patients who do not require mechanical ventilation or have incomplete medical records may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the timing of tracheostomy in patients with Guillain-Barre syndrome who require mechanical ventilation. It compares outcomes between patients who undergo early tracheostomy (within 7 days of intubation) and those who have late tracheostomy (after 7 days). The study aims to determine if early tracheostomy leads to reduced ventilation days, lower mortality rates, and shorter lengths of stay in both the hospital and ICU. The research is conducted at Meir Medical Center, focusing on critically ill patients with this condition.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for patients with Guillain-Barre syndrome requiring mechanical ventilation.

How similar studies have gone: Previous studies have shown mixed results regarding the timing of tracheostomy in critically ill patients, indicating that this approach may provide valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria: All patients aged 18--99 who were admitted to the general intensive care unit from January 2012 to September 2024 with a diagnosis of Guillain-Barre syndrome who required mechanical ventilation and underwent tracheostomy during ICU stay.

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Exclusion Criteria: Missing recoreded data

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Where it's running

  • Meir Medical Center
    Kfar Saba, Israel
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.