Comparing early and late tracheostomy in patients with Guillain-Barre syndrome
Official title: Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome: Comparison of Clinical Outcomes- a Retrospective Study
Run by Meir Medical Center · NCT06612242 · Data updated 2026-11-12
This study is testing if doing a tracheostomy sooner rather than later can help patients with Guillain-Barre syndrome who need breathing support recover faster and have better outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Meir Medical Center Academic / other |
| Locations | 1 site (Kfar Saba) |
| Status | Recruiting |
| Started | February 1, 2025 |
| Main results expected | January 1, 2027 |
| Study ends | January 1, 2027 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT06612242 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-99 diagnosed with Guillain-Barre syndrome who are admitted to the ICU and require mechanical ventilation.
✕Probably not a fit
Patients who do not require mechanical ventilation or have incomplete medical records may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the timing of tracheostomy in patients with Guillain-Barre syndrome who require mechanical ventilation. It compares outcomes between patients who undergo early tracheostomy (within 7 days of intubation) and those who have late tracheostomy (after 7 days). The study aims to determine if early tracheostomy leads to reduced ventilation days, lower mortality rates, and shorter lengths of stay in both the hospital and ICU. The research is conducted at Meir Medical Center, focusing on critically ill patients with this condition.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with Guillain-Barre syndrome requiring mechanical ventilation.
How similar studies have gone: Previous studies have shown mixed results regarding the timing of tracheostomy in critically ill patients, indicating that this approach may provide valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients aged 18--99 who were admitted to the general intensive care unit from January 2012 to September 2024 with a diagnosis of Guillain-Barre syndrome who required mechanical ventilation and underwent tracheostomy during ICU stay. \- Exclusion Criteria: Missing recoreded data \-
Where it's running
-
Meir Medical Center
Kfar Saba, Israel Recruiting
Study contacts
- Study coordinator: Sara Dichtwald, MD
- Email: sara.dichtwald@clalit.org.il
- Phone: 972-9-7472133
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.