Comparing early and late tracheostomy in patients with Guillain-Barre syndrome
Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome: Comparison of Clinical Outcomes- a Retrospective Study
This study is testing if doing a tracheostomy sooner rather than later can help patients with Guillain-Barre syndrome who need breathing support recover faster and have better outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Meir Medical Center Academic / other |
| Locations | 1 site (Kfar Saba) |
| Trial ID | NCT06612242 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the timing of tracheostomy in patients with Guillain-Barre syndrome who require mechanical ventilation. It compares outcomes between patients who undergo early tracheostomy (within 7 days of intubation) and those who have late tracheostomy (after 7 days). The study aims to determine if early tracheostomy leads to reduced ventilation days, lower mortality rates, and shorter lengths of stay in both the hospital and ICU. The research is conducted at Meir Medical Center, focusing on critically ill patients with this condition.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-99 diagnosed with Guillain-Barre syndrome who are admitted to the ICU and require mechanical ventilation.
Not a fit: Patients who do not require mechanical ventilation or have incomplete medical records may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with Guillain-Barre syndrome requiring mechanical ventilation.
How similar studies have performed: Previous studies have shown mixed results regarding the timing of tracheostomy in critically ill patients, indicating that this approach may provide valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients aged 18--99 who were admitted to the general intensive care unit from January 2012 to September 2024 with a diagnosis of Guillain-Barre syndrome who required mechanical ventilation and underwent tracheostomy during ICU stay. \- Exclusion Criteria: Missing recoreded data \-
Where this trial is running
Kfar Saba
- Meir Medical Center — Kfar Saba, Israel (Recruiting)
Study contacts
- Study coordinator: Sara Dichtwald, MD
- Email: sara.dichtwald@clalit.org.il
- Phone: 972-9-7472133
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.