Comparing different limb lengths in gastric bypass surgery for weight loss

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of limb length ratios in Roux-en-Y gastric bypass surgery on weight loss and metabolic outcomes in morbidly obese patients. Participants will be randomly assigned to receive either standard fixed-length gastric bypass or a ratio-adjusted version that customizes limb lengths based on the patient's total small bowel length. The study aims to determine if the ratio-adjusted approach leads to greater total weight loss and improved resolution of metabolic syndrome comorbidities, such as diabetes and hypertension. Quality of life metrics will also be assessed postoperatively using the SF36 survey.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* morbidly obese patients (defined by BMI between 40 and 60).
* Patient who understands and accepts the need for a long-term follow-up.
* Patient who agrees to be included in the study

Exclusion Criteria:

* individuals unable to understand and sign a written consent form
* patients with history of previous bariatric surgery procedures
* presence of a severe and evolutive life threatening pathology unrelated to obesity
* previous gastric or small bowel resection
* active cancer
* pregnancy or desired to be pregnant during the study
* mentally unbalanced patients under supervision or guardianship, patient unable to give consent

Where it's running

• Cleveland clinic
  Cleveland, Ohio, United States Recruiting

Study contacts

• Principal investigator: Salvador Navarrete, MD — The Cleveland Clinic
• Study coordinator: Salvador Navarrete, MD
• Email: navarrs@ccf.org
• Phone: 2162199211

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• TSBL-based vs BMI-based limb length in one-anastomosis gastric bypass

  This trial tests whether calculating the biliopancreatic limb length by total small bowel length (TSBL) helps weight loss and safety more than using standard BMI-based lengths in adults undergoing a single-center OAGB for obesity.

  Recruiting National Scientific Center of Surgery named after A.N.Syzganov · Almaty · NCT07796503

• Gut stool tests after sleeve vs gastric bypass

  This study tests whether routine stool tests can reveal changes in gut function six months after sleeve gastrectomy or gastric bypass in adults with morbid obesity.

  Recruiting Cairo University · Cairo, Al-Manial Cairo · NCT07461610

• Impact of Bariatric Surgery on Female Sexual Function and Hormones

  This observational study will see how weight loss surgery affects sexual function and hormone levels in women with severe obesity, six months after surgery.

  Recruiting Cairo University · Cairo, Al-Manial Cairo · NCT07446972

• Dual-chamber patient-controlled pain relief after laparoscopic sleeve gastrectomy

  This test checks whether a dual-chamber IV patient-controlled pump delivering fentanyl plus ketorolac reduces pain and postoperative nausea and vomiting in adults having laparoscopic sleeve gastrectomy.

  Recruiting Seoul National University Bundang Hospital · Seongnam-si, Gyunggi-do · NCT07051109

• Exercise program to improve weight, strength, and recovery around bariatric surgery

  This program will test whether a structured exercise plan supported by telerehabilitation helps adults with severe obesity who are having bariatric surgery lose more body fat and gain more strength than usual care.

  Recruiting Instituto de Investigacion Sanitaria La Fe · Valencia, Valencia and 1 other locations · NCT06934681

• Comparing rivaroxaban and enoxaparin for preventing blood clots in obese patients undergoing weight loss surgery

  This study tests whether the blood thinner rivaroxaban works better than enoxaparin to prevent blood clots in obese patients having weight loss surgery.

  Recruiting Alexandria University · Alexandria · NCT06689241

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.