Comparing different flexible ureteroscopes for treating kidney stones
Comparing Different Diameter fURSs With Similar RESDs for the Treatment of Upper Urinary Tract Stones - A Randomized Controlled Multi-center Clinical Trials
NA · Ningbo No. 1 Hospital · NCT06987760
This study is testing which size of flexible ureteroscope works best for treating kidney stones in adults aged 18 to 80.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 206 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Ningbo No. 1 Hospital (other) |
| Locations | 1 site (Ningbo, Zhejiang) |
| Trial ID | NCT06987760 on ClinicalTrials.gov |
What this trial studies
This study evaluates the efficiency, effectiveness, and safety of flexible ureteroscope (fURS) lithotripsy for patients with upper urinary tract stones. It specifically compares different diameters of fURS with similar retrograde endoscope diameters (RESDs) to determine the best approach for treatment. Patients aged 18 to 80 with kidney stones less than 3 cm in diameter will be included, while those with certain medical conditions or prior surgeries will be excluded. The study aims to provide insights into optimizing treatment for urolithiasis.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 with kidney or upper ureteral stones less than 3 cm in diameter.
Not a fit: Patients with a history of ureteral stenosis, severe hydronephrosis, or those undergoing simultaneous surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients suffering from kidney stones.
How similar studies have performed: Other studies have shown promising results with flexible ureteroscopes in treating urolithiasis, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- 1.Patients with kidney stones or upper ureteral stones with a cumulative diameter of less than 3 cm are selected for ureteral soft lens holmium laser lithotripsy. 2.Age 18 to 80 years old, gender unlimited. 3.The subjects have no mental illness or language dysfunction, can understand the situation of the study and can sign informed consent. Exclusion Criteria: * 1.Patients with a history of ureteral stenosis or who have undergone open or laparoscopic ureteral or renal lithotomy. 2.Patients with fever one week before surgery 3.Pregnant women and menstruating patients. 4.Patients with combined systemic disease or inability to tolerate anesthesia. 5.Patients undergoing simultaneous surgery for bilateral upper urinary tract stones. 6.Patients with ureteral stent indwelling before surgery. 7.In patients with severe hydronephrosis, the separation of the renal collecting system is greater than 4 cm. 8.Patients with renal anatomic malformations such as polycystic kidney, horseshoe kidney, and ectopic kidney.
Where this trial is running
Ningbo, Zhejiang
- The First Affiliated Hospital of Ningbo University — Ningbo, Zhejiang, China (RECRUITING)
Study contacts
- Study coordinator: Li Fang
- Email: fanyruo@126.com
- Phone: +86-13586681743
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ureter Injury, Urolithiasis, Lower Urinary Tract, Efficacy, Self, Ratio of Endoscope-Sheath Diameter, Flexible ureteroscope