Comparing different flexible ureteroscopes for treating kidney stones
Official title: Comparing Different Diameter fURSs With Similar RESDs for the Treatment of Upper Urinary Tract Stones - A Randomized Controlled Multi-center Clinical Trials
Run by Ningbo No. 1 Hospital · NCT06987760 · Data updated 2026-11-12
This study is testing which size of flexible ureteroscope works best for treating kidney stones in adults aged 18 to 80.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 206 (estimated) |
| Sponsor | Ningbo No. 1 Hospital Academic / other |
| Locations | 1 site (Ningbo, Zhejiang) |
| Status | Recruiting |
| Started | March 19, 2025 |
| Main results expected | September 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | May 23, 2025 |
| Trial ID | NCT06987760 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 80 with kidney or upper ureteral stones less than 3 cm in diameter.
✕Probably not a fit
Patients with a history of ureteral stenosis, severe hydronephrosis, or those undergoing simultaneous surgeries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the efficiency, effectiveness, and safety of flexible ureteroscope (fURS) lithotripsy for patients with upper urinary tract stones. It specifically compares different diameters of fURS with similar retrograde endoscope diameters (RESDs) to determine the best approach for treatment. Patients aged 18 to 80 with kidney stones less than 3 cm in diameter will be included, while those with certain medical conditions or prior surgeries will be excluded. The study aims to provide insights into optimizing treatment for urolithiasis.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients suffering from kidney stones.
How similar studies have gone: Other studies have shown promising results with flexible ureteroscopes in treating urolithiasis, indicating that this approach is supported by existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- 1.Patients with kidney stones or upper ureteral stones with a cumulative diameter of less than 3 cm are selected for ureteral soft lens holmium laser lithotripsy. 2.Age 18 to 80 years old, gender unlimited. 3.The subjects have no mental illness or language dysfunction, can understand the situation of the study and can sign informed consent. Exclusion Criteria: * 1.Patients with a history of ureteral stenosis or who have undergone open or laparoscopic ureteral or renal lithotomy. 2.Patients with fever one week before surgery 3.Pregnant women and menstruating patients. 4.Patients with combined systemic disease or inability to tolerate anesthesia. 5.Patients undergoing simultaneous surgery for bilateral upper urinary tract stones. 6.Patients with ureteral stent indwelling before surgery. 7.In patients with severe hydronephrosis, the separation of the renal collecting system is greater than 4 cm. 8.Patients with renal anatomic malformations such as polycystic kidney, horseshoe kidney, and ectopic kidney.
Where it's running
-
The First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Li Fang
- Email: fanyruo@126.com
- Phone: +86-13586681743
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Acupressure to Ease Pain During ESWL for Kidney Stones
This study tests whether applying acupressure to specific points before ESWL can reduce pain and improve comfort for adults with kidney or proximal ureteral stones.
-
Audio consent with human voice or AI-voice added to written consent for ureteroscopy
This study tests if listening to an audio version of the consent form, read by a real urologist or by an AI-cloned voice, helps adults in Turkey understand their ureteroscopy or RIRS consent better than the written form alone.
-
Norepinephrine irrigation to help stop bleeding during flexible ureteroscopic lithotripsy
This study tests whether a norepinephrine-powered irrigation solution can help control bleeding during flexible ureteroscopic lithotripsy for upper urinary tract stones in adults.
-
Long-term safety of UAS-assisted vs sheathless RIRS in adults with kidney stones
This study tests whether using a ureteral access sheath during the initial RIRS affects long-term safety and outcomes in adults with kidney stones ≤20 mm.
-
See if pelvic floor endurance relates to stent symptoms after ureteroscopy
This study tests whether a ultrasound measure of pelvic floor endurance (PFFI) can predict ureteral stent-related symptoms after ureteroscopy or RIRS in adults 18–65.
-
Aspiration-enabled vs conventional ureteral access sheath for RIRS in kidney stone patients
This study tests whether using an aspiration-enabled access sheath during retrograde intrarenal surgery (RIRS) helps prevent early kidney injury compared with conventional sheaths in adults with kidney stones.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.