Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Comparing different flexible ureteroscopes for treating kidney stones

Official title: Comparing Different Diameter fURSs With Similar RESDs for the Treatment of Upper Urinary Tract Stones - A Randomized Controlled Multi-center Clinical Trials

Run by Ningbo No. 1 Hospital · NCT06987760 · Data updated 2026-11-12

This study is testing which size of flexible ureteroscope works best for treating kidney stones in adults aged 18 to 80.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment206 (estimated)
SponsorNingbo No. 1 Hospital
Academic / other
Locations1 site (Ningbo, Zhejiang)
StatusRecruiting
StartedMarch 19, 2025
Main results expectedSeptember 30, 2026
Study endsDecember 30, 2026
Registry record updatedMay 23, 2025
Trial IDNCT06987760 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 80 with kidney or upper ureteral stones less than 3 cm in diameter.

Probably not a fit

Patients with a history of ureteral stenosis, severe hydronephrosis, or those undergoing simultaneous surgeries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the efficiency, effectiveness, and safety of flexible ureteroscope (fURS) lithotripsy for patients with upper urinary tract stones. It specifically compares different diameters of fURS with similar retrograde endoscope diameters (RESDs) to determine the best approach for treatment. Patients aged 18 to 80 with kidney stones less than 3 cm in diameter will be included, while those with certain medical conditions or prior surgeries will be excluded. The study aims to provide insights into optimizing treatment for urolithiasis.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment options for patients suffering from kidney stones.

How similar studies have gone: Other studies have shown promising results with flexible ureteroscopes in treating urolithiasis, indicating that this approach is supported by existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- 1.Patients with kidney stones or upper ureteral stones with a cumulative diameter of less than 3 cm are selected for ureteral soft lens holmium laser lithotripsy.

2.Age 18 to 80 years old, gender unlimited. 3.The subjects have no mental illness or language dysfunction, can understand the situation of the study and can sign informed consent.

Exclusion Criteria:

* 1.Patients with a history of ureteral stenosis or who have undergone open or laparoscopic ureteral or renal lithotomy.

  2.Patients with fever one week before surgery 3.Pregnant women and menstruating patients. 4.Patients with combined systemic disease or inability to tolerate anesthesia. 5.Patients undergoing simultaneous surgery for bilateral upper urinary tract stones.

  6.Patients with ureteral stent indwelling before surgery. 7.In patients with severe hydronephrosis, the separation of the renal collecting system is greater than 4 cm.

  8.Patients with renal anatomic malformations such as polycystic kidney, horseshoe kidney, and ectopic kidney.

Where it's running

  • The First Affiliated Hospital of Ningbo University
    Ningbo, Zhejiang, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.