Comparing Dexmedetomidine and Magnesium Sulphate for Pain Relief After Thoracotomy
Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain
NA · National Cancer Institute, Egypt · NCT05851768
This study is testing whether adding dexmedetomidine or magnesium to a common pain medication can help people feel less pain after thoracotomy surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | National Cancer Institute, Egypt (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05851768 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of dexmedetomidine versus magnesium sulphate when combined with bupivacaine in providing pain relief through an erector spinae block for patients undergoing thoracotomy. The goal is to enhance postoperative analgesia and reduce complications associated with thoracotomy. Participants will receive one of three interventions: bupivacaine alone, bupivacaine with magnesium, or bupivacaine with dexmedetomidine. The study aims to determine which combination offers superior pain management.
Who should consider this trial
Good fit: Ideal candidates are cancer patients aged 18 to 65 years, classified as ASA I-III, with a BMI between 18.5 and 30 kg/m2.
Not a fit: Patients who refuse participation or have known allergies to the study drugs, low platelet counts, or coagulation defects may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracotomy.
How similar studies have performed: While there is ongoing research in regional analgesia techniques, this specific comparison of dexmedetomidine and magnesium sulphate in the context of thoracotomy pain management is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 18 to 65 years. * Male and female sexes. * ASA I-II.,III * Cancer patients undergoing thoracotomy incisions * Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: * Patient refusal * Known allergy to any of the used drugs * Low platelet count, any coagulation defect
Where this trial is running
Cairo
- Walaa Y Elsabeeny — Cairo, Egypt (RECRUITING)
Study contacts
- Principal investigator: Walaa Y Elsabeeny, MD — Assistant professor of Anesthesia and Pain Management, National Cancer Institute, Cairo University
- Study coordinator: Walaa Y Elsabeeny, MD
- Email: walaa.elsabeeny@nci.cu.edu.eg
- Phone: 01007798466
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Analgesia