Comparing Dexmedetomidine and Magnesium Sulphate for Pain Relief After Thoracotomy
Official title: Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain
Run by National Cancer Institute, Egypt · NCT05851768 · Data updated 2026-11-12
This study is testing whether adding dexmedetomidine or magnesium to a common pain medication can help people feel less pain after thoracotomy surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | National Cancer Institute, Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | May 15, 2023 |
| Main results expected | November 25, 2026 |
| Study ends | December 27, 2026 |
| Registry record updated | June 30, 2026 |
| Trial ID | NCT05851768 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are cancer patients aged 18 to 65 years, classified as ASA I-III, with a BMI between 18.5 and 30 kg/m2.
✕Probably not a fit
Patients who refuse participation or have known allergies to the study drugs, low platelet counts, or coagulation defects may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of dexmedetomidine versus magnesium sulphate when combined with bupivacaine in providing pain relief through an erector spinae block for patients undergoing thoracotomy. The goal is to enhance postoperative analgesia and reduce complications associated with thoracotomy. Participants will receive one of three interventions: bupivacaine alone, bupivacaine with magnesium, or bupivacaine with dexmedetomidine. The study aims to determine which combination offers superior pain management.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracotomy.
How similar studies have gone: While there is ongoing research in regional analgesia techniques, this specific comparison of dexmedetomidine and magnesium sulphate in the context of thoracotomy pain management is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 18 to 65 years. * Male and female sexes. * ASA I-II.,III * Cancer patients undergoing thoracotomy incisions * Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: * Patient refusal * Known allergy to any of the used drugs * Low platelet count, any coagulation defect
Where it's running
-
Walaa Y Elsabeeny
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Walaa Y Elsabeeny, MD — Assistant professor of Anesthesia and Pain Management, National Cancer Institute, Cairo University
- Study coordinator: Walaa Y Elsabeeny, MD
- Email: walaa.elsabeeny@nci.cu.edu.eg
- Phone: 01007798466
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.