Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Comparing Dexmedetomidine and Magnesium Sulphate for Pain Relief After Thoracotomy

Official title: Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain

Run by National Cancer Institute, Egypt · NCT05851768 · Data updated 2026-11-12

This study is testing whether adding dexmedetomidine or magnesium to a common pain medication can help people feel less pain after thoracotomy surgery.

More Analgesia trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment60 (estimated)
SponsorNational Cancer Institute, Egypt
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedMay 15, 2023
Main results expectedNovember 25, 2026
Study endsDecember 27, 2026
Registry record updatedJune 30, 2026
Trial IDNCT05851768 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are cancer patients aged 18 to 65 years, classified as ASA I-III, with a BMI between 18.5 and 30 kg/m2.

Probably not a fit

Patients who refuse participation or have known allergies to the study drugs, low platelet counts, or coagulation defects may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of dexmedetomidine versus magnesium sulphate when combined with bupivacaine in providing pain relief through an erector spinae block for patients undergoing thoracotomy. The goal is to enhance postoperative analgesia and reduce complications associated with thoracotomy. Participants will receive one of three interventions: bupivacaine alone, bupivacaine with magnesium, or bupivacaine with dexmedetomidine. The study aims to determine which combination offers superior pain management.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracotomy.

How similar studies have gone: While there is ongoing research in regional analgesia techniques, this specific comparison of dexmedetomidine and magnesium sulphate in the context of thoracotomy pain management is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age from 18 to 65 years.
* Male and female sexes.
* ASA I-II.,III
* Cancer patients undergoing thoracotomy incisions
* Body mass index (BMI) from 18.5 to 30 kg/m2

Exclusion Criteria:

* Patient refusal
* Known allergy to any of the used drugs
* Low platelet count, any coagulation defect

Where it's running

  • Walaa Y Elsabeeny
    Cairo, Egypt
    Recruiting

Study contacts

  • Principal investigator: Walaa Y Elsabeeny, MD — Assistant professor of Anesthesia and Pain Management, National Cancer Institute, Cairo University
  • Study coordinator: Walaa Y Elsabeeny, MD
  • Email: walaa.elsabeeny@nci.cu.edu.eg
  • Phone: 01007798466

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.