Comparing Dexamethasone and Dexmedetomidine for Pain Relief After Spine Surgery
Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery
This study is testing whether using Dexamethasone or Dexmedetomidine can help reduce pain and speed up recovery for patients after spine surgery.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Poznan University of Medical Sciences Academic / other |
| Locations | 1 site (Poznan, Poznań) |
| Trial ID | NCT06233617 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of perineural Dexamethasone and Dexmedetomidine on the duration of erector spinae plane blocks in patients undergoing spine surgery. The goal is to enhance postoperative pain management while ensuring safety by potentially allowing for lower doses of local anesthetics. By comparing these two adjuvants, the study aims to identify which provides better analgesia and faster recovery for patients after spinal procedures. The research addresses a significant gap in existing literature regarding their use specifically in spine surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 100 years undergoing primary posterior lumbar decompression and stabilization with instrumentation.
Not a fit: Patients with a history of opioid abuse or those with ASA physical status 4 or 5 may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing spine surgery.
How similar studies have performed: While there is considerable research on the use of Dexamethasone and Dexmedetomidine in other contexts, this specific application in spine surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients undergoing primary posterior lumbar decompression and stabilization with instrumentation involving multi-levels in the lumbar region, * aged \>18 years and \<100 years * ASA physical status 1, 2 or 3. Exclusion Criteria: * refuse to participate, * history of opioid abuse, * infection of the puncture site, * aged \<18 years and \>100 years * ASA 4 and 5
Where this trial is running
Poznan, Poznań
- Poznan University of Medical Sciences — Poznan, Poznań, Poland (Recruiting)
Study contacts
- Principal investigator: Malgorzata Domagalska, PhD — Poznań University of Medical Sciences
- Study coordinator: Malgorzata Domagalska, PhD
- Email: m.domagalska@icloud.com
- Phone: +48 61 873 83 03
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.