Comparing Dexamethasone and Dexmedetomidine for Pain Management After Hip Surgery
Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty
This study is testing whether Dexamethasone or Dexmedetomidine can help manage pain better after hip surgery, so patients can recover faster with less need for strong pain medicine.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Poznan University of Medical Sciences Academic / other |
| Locations | 1 site (Poznan, Poznań) |
| Trial ID | NCT06233604 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of perineurial Dexamethasone and Dexmedetomidine on the duration of erector spinal plane blocks in patients undergoing hip arthroplasty. The goal is to enhance postoperative pain management while ensuring safety by potentially allowing for lower doses of local anesthetics. By comparing these two adjuvants, the study aims to identify which provides better pain relief and faster recovery. This research addresses a significant gap in existing literature regarding their use in spine surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 100 years undergoing primary hip arthroplasty with ASA physical status 1, 2, or 3.
Not a fit: Patients with severe comorbidities, such as ASA 4 or 5, or those with a history of opioid abuse will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip arthroplasty.
How similar studies have performed: While there is considerable research on dexamethasone and dexmedetomidine in other contexts, this specific application in spine surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients undergoing primary hip arthroplasty * aged \>18 years and \<100 years * ASA physical status 1, 2 or 3. Exclusion Criteria: * if they refused to participate, * had a history of opioid abuse, * had an infection of the site of needle puncture, * were less than 18 years of age, * were postponed as having ASA 4 or 5, * had an allergy to any of the drugs used in the study, * renal failure (estimated glomerular filtration rate \<15ml/min/1.73m2), * liver failure, * known or suspected coagulopathy, * pre-existing anatomical or neurological disorders in the lower extremities, * intellectual disability with problems in pain evaluation, * severe psychiatric illness.
Where this trial is running
Poznan, Poznań
- Poznan University of Medical Sciences — Poznan, Poznań, Poland (Recruiting)
Study contacts
- Study coordinator: Malgorzata Domagalska, Ph.D.
- Email: m.domagalska@icloud.com
- Phone: +48 61 873 83 03
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.