Comparing delirium rates from different anesthetics in liver transplant patients
Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation
This study is testing whether using different types of anesthesia during liver transplant surgery can help reduce the chances of patients experiencing delirium afterward.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 350 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Yonsei University Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06767579 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the incidence of postoperative delirium in patients undergoing liver transplantation. It focuses on comparing the effects of two anesthetic agents: the inhalational anesthetic sevoflurane and the intravenous anesthetic propofol. By analyzing patient outcomes, the study aims to identify which anesthetic may be associated with a lower incidence of delirium. The study will include adults aged 19 and older who are scheduled for liver transplantation and will exclude individuals with certain cognitive impairments or neurological disorders.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 19 and older who are scheduled to undergo liver transplantation.
Not a fit: Patients with cognitive impairments, neurological disorders, or communication difficulties may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify anesthetic practices that minimize the risk of delirium in liver transplant patients.
How similar studies have performed: Other studies have explored the effects of different anesthetics on postoperative outcomes, suggesting that this approach has potential based on prior findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 19 years and older * Patients undergoing liver transplantation who are scheduled to receive anesthesia with the inhaled anesthetic sevoflurane or the intravenous anesthetic propofol. Exclusion Criteria: * Individuals with hearing loss, cognitive impairment or obvious dementia, hepatic encephalopathy, or difficulty in communication. * Diagnosed with neurological disorders (e.g., brain hemorrhage, stroke, dementia, Parkinson's disease, cognitive impairment, etc.).
Where this trial is running
Seoul
- Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine — Seoul, South Korea (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.