Clinical trial Recruiting at 1 site Observational Ages 19 and up

Comparing delirium rates from different anesthetics in liver transplant patients

Official title: Comparison of the Incidence of Delirium Caused by Different Anesthetic Agents in Patients Undergoing Liver Transplantation

Run by Yonsei University · NCT06767579 · Data updated 2026-11-12

This study is testing whether using different types of anesthesia during liver transplant surgery can help reduce the chances of patients experiencing delirium afterward.

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Quick facts

Study typeObservational
Ages19 Years and up
SexAll
Enrollment350 (estimated)
SponsorYonsei University
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedOctober 24, 2024
Main results expectedOctober 28, 2027
Study endsOctober 17, 2028
Registry record updatedJanuary 10, 2025
Trial IDNCT06767579 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 19 and older who are scheduled to undergo liver transplantation.

Probably not a fit

Patients with cognitive impairments, neurological disorders, or communication difficulties may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the incidence of postoperative delirium in patients undergoing liver transplantation. It focuses on comparing the effects of two anesthetic agents: the inhalational anesthetic sevoflurane and the intravenous anesthetic propofol. By analyzing patient outcomes, the study aims to identify which anesthetic may be associated with a lower incidence of delirium. The study will include adults aged 19 and older who are scheduled for liver transplantation and will exclude individuals with certain cognitive impairments or neurological disorders.

Why it matters

Potential benefit: If successful, this study could help identify anesthetic practices that minimize the risk of delirium in liver transplant patients.

How similar studies have gone: Other studies have explored the effects of different anesthetics on postoperative outcomes, suggesting that this approach has potential based on prior findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 19 years and older
* Patients undergoing liver transplantation who are scheduled to receive anesthesia with the inhaled anesthetic sevoflurane or the intravenous anesthetic propofol.

Exclusion Criteria:

* Individuals with hearing loss, cognitive impairment or obvious dementia, hepatic encephalopathy, or difficulty in communication.
* Diagnosed with neurological disorders (e.g., brain hemorrhage, stroke, dementia, Parkinson's disease, cognitive impairment, etc.).

Where it's running

  • Department of Anesthesiology and Pain Medicine Yonsei University College of Medicine
    Seoul, South Korea
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.