Comparing defibrillation techniques for out-of-hospital cardiac arrest

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The STRAT-DEFI trial investigates different defibrillation strategies for adults experiencing out-of-hospital cardiac arrest. It compares standard anterior-lateral pad positioning with anterior-posterior positioning and double-sequential defibrillation. Participants are randomly assigned to one of three groups to evaluate the effectiveness of these techniques in restoring normal heart rhythm. The trial aims to determine which method yields the best outcomes for patients in critical situations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Out-of-hospital cardiac arrest
2. Age ≥ 18 years
3. ≥ 1 manual defibrillation attempt by emergency medical services
4. Shockable rhythm as the last known rhythm
5. Two manual defibrillators present on-site

Exclusion Criteria:

1. Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of the cardiac arrest
2. Prior enrollment in the trial
3. Posterior pad placement not deemed possible by on-site clinician

Where it's running

• Emergency Medical Services, the North Denmark Region
  Aalborg, Denmark Recruiting
• Prehospital Emergency Medical Services, Central Denmark Region
  Aarhus N, Denmark Recruiting
• Danish Air Ambulance, Danish Regions
  Aarhus N, Denmark Not yet recruiting
• Copenhagen Emergency Medical Services, the Capital Region of Denmark
  Ballerup Municipality, Denmark Not yet recruiting
• The Prehospital Center, Region Zealand
  Næstved, Denmark Not yet recruiting
• Emergency Medical Services, the Region of Southern Denmark
  Vejle, Denmark Not yet recruiting

Study contacts

• Study coordinator: Lars W Andersen
• Email: lwandersen@clin.au.dk
• Phone: +4578414848

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.