Comparing cytokine levels in eye fluids before and after a specific glaucoma treatment
Official title: Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment
Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT06243497 · Data updated 2026-11-12
This study is testing how a glaucoma treatment called Ultrasound Cyclo Plasty affects certain proteins in the eye fluids of patients to see if it helps manage their condition better.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | February 1, 2024 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | February 6, 2024 |
| Trial ID | NCT06243497 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with glaucoma who have elevated intraocular pressure or progressive optic nerve damage.
✕Probably not a fit
Patients with other eye diseases affecting intraocular pressure or those who have had recent anti-glaucoma surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare the profiles of cytokines in the aqueous humor and tears of patients diagnosed with glaucoma before and after undergoing Ultrasound Cyclo Plasty (UCP). UCP is a minimally invasive technique that targets the ciliary body to manage intraocular pressure (IOP), which is crucial for glaucoma treatment. By analyzing the changes in cytokine levels, the study seeks to understand the pathophysiological changes associated with glaucoma and the effectiveness of UCP. The findings could provide insights into potential biomarkers for glaucoma management.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of glaucoma treatment and lead to improved management strategies for patients.
How similar studies have gone: Previous studies have shown promising results in understanding the role of cytokines in glaucoma, suggesting that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * The patient was definitely diagnosed as glaucoma, No age or gender limitation, IOP(intraocular pressure) ≥ 21mmHg under the maximum tolerated dose of antiglaucoma medication, or IOP \< 21mmHg and glaucomatous optic nerve damage progressed. Exclusion Criteria: * Other eye diseases that could affect IOP; preoperative use of systemic steroid drugs; history of other anti-glaucoma surgery within 3 months; ocular infection 2 weeks prior to UCP
Where it's running
-
Zhognshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, Guangdong, China Recruiting
Study contacts
- Study coordinator: HuanYang Shi, M.D
- Email: shyhuanyang@163.com
- Phone: +8602066615461
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.