Clinical trial Recruiting at 1 site Observational

Comparing cytokine levels in eye fluids before and after a specific glaucoma treatment

Official title: Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment

Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT06243497 · Data updated 2026-11-12

This study is testing how a glaucoma treatment called Ultrasound Cyclo Plasty affects certain proteins in the eye fluids of patients to see if it helps manage their condition better.

More Glaucoma trials

Quick facts

Study typeObservational
SexAll
Enrollment200 (estimated)
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedFebruary 1, 2024
Main results expectedFebruary 1, 2027
Study endsFebruary 1, 2027
Registry record updatedFebruary 6, 2024
Trial IDNCT06243497 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with glaucoma who have elevated intraocular pressure or progressive optic nerve damage.

Probably not a fit

Patients with other eye diseases affecting intraocular pressure or those who have had recent anti-glaucoma surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the profiles of cytokines in the aqueous humor and tears of patients diagnosed with glaucoma before and after undergoing Ultrasound Cyclo Plasty (UCP). UCP is a minimally invasive technique that targets the ciliary body to manage intraocular pressure (IOP), which is crucial for glaucoma treatment. By analyzing the changes in cytokine levels, the study seeks to understand the pathophysiological changes associated with glaucoma and the effectiveness of UCP. The findings could provide insights into potential biomarkers for glaucoma management.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of glaucoma treatment and lead to improved management strategies for patients.

How similar studies have gone: Previous studies have shown promising results in understanding the role of cytokines in glaucoma, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patient was definitely diagnosed as glaucoma, No age or gender limitation, IOP(intraocular pressure) ≥ 21mmHg under the maximum tolerated dose of antiglaucoma medication, or IOP \< 21mmHg and glaucomatous optic nerve damage progressed.

Exclusion Criteria:

* Other eye diseases that could affect IOP; preoperative use of systemic steroid drugs; history of other anti-glaucoma surgery within 3 months; ocular infection 2 weeks prior to UCP

Where it's running

  • Zhognshan Ophthalmic Center, Sun Yat-sen University
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.