Comparing corticosteroid injections and nerve blocks for shoulder pain relief
Official title: A Randomized Comparative Cohort Study of the Use of Intra-articular Corticosteroid Injection Compared to Suprascapular Nerve Block for Treatment of Shoulder Pain
Run by University of Minnesota · NCT06735027 · Data updated 2026-11-12
This study tests whether corticosteroid injections or nerve blocks work better to relieve shoulder pain for people with arthritis or rotator cuff issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Status | Recruiting |
| Started | January 2, 2025 |
| Main results expected | January 2, 2027 |
| Study ends | January 2, 2027 |
| Registry record updated | January 8, 2026 |
| Trial ID | NCT06735027 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults diagnosed with glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are considering injection therapy.
✕Probably not a fit
Patients with uncontrolled diabetes, known allergies to steroids or anesthetics, or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates two conservative pain relief methods for patients with glenohumeral arthritis or rotator cuff arthropathy. It compares the effectiveness of intraarticular corticosteroid injections with suprascapular nerve blocks as analgesic options. The goal is to determine which method provides better pain relief for these conditions. This research aims to enhance treatment strategies for managing osteoarthritis-related shoulder pain.
Why it matters
Potential benefit: If successful, this study could provide patients with more effective pain management options for shoulder conditions.
How similar studies have gone: While corticosteroid injections are commonly used, the use of suprascapular nerve blocks in this context is less frequently studied, making this approach somewhat novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are being offered injection Exclusion Criteria: * uncontrolled diabetes (patients will be excluded if no HbA1c within a year or if it is 8 or greater" * known allergy to steroid or anesthetic * pregnant women * prisoners * patients with diminished capacity to consent to participation * children under 18 years of age * non-English speakers
Where it's running
-
University of Minnesota
Minneapolis, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Allison Rao, MD — University of Minnesota
- Study coordinator: Allison Rao
- Email: rao00149@umn.edu
- Phone: 608-445-0545
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Tipmed Shoulder Prosthesis PMCF: safety and outcomes after shoulder replacement
This PMCF study tests the safety and function of the Tipmed shoulder prosthesis in adults undergoing reverse shoulder or hemiarthroplasty in real-world practice.
-
Long-term follow-up of FX Shoulder Solutions implants
This follow-up will track adults who receive FX Shoulder Solutions hemi or total shoulder replacements to see if the implants need revision and how well shoulder function and pain hold up over 10 years.
-
Comparing shoulder surgery to exercise for rotator cuff problems
This study tests whether shoulder surgery or a 12-week exercise program works better for people with rotator cuff problems.
-
Comparing pectoralis minor release with no release during shoulder surgery
This study tests if releasing a specific shoulder muscle during surgery can help people feel less pain and move their shoulder better after getting a reverse shoulder replacement.
-
Observing outcomes of the Medacta Shoulder System
This study is looking at how well the Medacta Shoulder System works and its safety for people with different shoulder problems.
-
Long-term follow-up on shoulder arthroplasty outcomes
This study is looking at how well shoulder replacement surgery works over time by following patients for at least 10 years to see how they feel and how their shoulders are doing.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.