Clinical trial Recruiting at 1 site Interventional Ages 18 to 99

Comparing corticosteroid injections and nerve blocks for shoulder pain relief

Official title: A Randomized Comparative Cohort Study of the Use of Intra-articular Corticosteroid Injection Compared to Suprascapular Nerve Block for Treatment of Shoulder Pain

Run by University of Minnesota · NCT06735027 · Data updated 2026-11-12

This study tests whether corticosteroid injections or nerve blocks work better to relieve shoulder pain for people with arthritis or rotator cuff issues.

More Rotator Cuff Tear Arthropathy trials

Quick facts

Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment40 (estimated)
SponsorUniversity of Minnesota
Academic / other
Locations1 site (Minneapolis, Minnesota)
StatusRecruiting
StartedJanuary 2, 2025
Main results expectedJanuary 2, 2027
Study endsJanuary 2, 2027
Registry record updatedJanuary 8, 2026
Trial IDNCT06735027 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults diagnosed with glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are considering injection therapy.

Probably not a fit

Patients with uncontrolled diabetes, known allergies to steroids or anesthetics, or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates two conservative pain relief methods for patients with glenohumeral arthritis or rotator cuff arthropathy. It compares the effectiveness of intraarticular corticosteroid injections with suprascapular nerve blocks as analgesic options. The goal is to determine which method provides better pain relief for these conditions. This research aims to enhance treatment strategies for managing osteoarthritis-related shoulder pain.

Why it matters

Potential benefit: If successful, this study could provide patients with more effective pain management options for shoulder conditions.

How similar studies have gone: While corticosteroid injections are commonly used, the use of suprascapular nerve blocks in this context is less frequently studied, making this approach somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosis of glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are being offered injection

Exclusion Criteria:

* uncontrolled diabetes (patients will be excluded if no HbA1c within a year or if it is 8 or greater"
* known allergy to steroid or anesthetic
* pregnant women
* prisoners
* patients with diminished capacity to consent to participation
* children under 18 years of age
* non-English speakers

Where it's running

  • University of Minnesota
    Minneapolis, Minnesota, United States
    Recruiting

Study contacts

  • Principal investigator: Allison Rao, MD — University of Minnesota
  • Study coordinator: Allison Rao
  • Email: rao00149@umn.edu
  • Phone: 608-445-0545

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Tipmed Shoulder Prosthesis PMCF: safety and outcomes after shoulder replacement

    This PMCF study tests the safety and function of the Tipmed shoulder prosthesis in adults undergoing reverse shoulder or hemiarthroplasty in real-world practice.

    Recruiting TIPMED Medical Device Manufacturing Ltd. Co. · Balıkesir and 3 other locations · NCT07678034

  • Long-term follow-up of FX Shoulder Solutions implants

    This follow-up will track adults who receive FX Shoulder Solutions hemi or total shoulder replacements to see if the implants need revision and how well shoulder function and pain hold up over 10 years.

    Recruiting at 22 sites FX Solutions · Amiens and 21 other locations · NCT07558590

  • Comparing shoulder surgery to exercise for rotator cuff problems

    This study tests whether shoulder surgery or a 12-week exercise program works better for people with rotator cuff problems.

    Recruiting at 8 sites University of Aarhus · Aarhus N and 7 other locations · NCT04864158

  • Comparing pectoralis minor release with no release during shoulder surgery

    This study tests if releasing a specific shoulder muscle during surgery can help people feel less pain and move their shoulder better after getting a reverse shoulder replacement.

    Recruiting at 2 sites Emory University · Atlanta, Georgia and 1 other locations · NCT06292169

  • Observing outcomes of the Medacta Shoulder System

    This study is looking at how well the Medacta Shoulder System works and its safety for people with different shoulder problems.

    Recruiting Medacta International SA · Annecy · NCT05926622

  • Long-term follow-up on shoulder arthroplasty outcomes

    This study is looking at how well shoulder replacement surgery works over time by following patients for at least 10 years to see how they feel and how their shoulders are doing.

    Recruiting at 40 sites Exactech · Laguna Woods, California and 39 other locations · NCT05603728

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.