Comparing continuous and intermittent blood pressure monitoring to prevent organ failure after surgery

Continuous Vs Intermittent Non Invasive Blood Pressure Monitoring in Preventing Post Operative Organ Failure

Not applicable Interventional University of Messina · NCT05496322

This study tests if continuous blood pressure monitoring during surgery can help prevent organ failure better than the usual method of checking blood pressure at intervals for adults having non-cardiac surgeries.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1265 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Messina Academic / other
Locations1 site (Messina)
Trial IDNCT05496322 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of continuous non-invasive blood pressure monitoring compared to traditional intermittent monitoring in preventing postoperative organ failure. It aims to determine whether continuous monitoring can reduce the duration of hypotensive and hypertensive episodes during surgery, potentially leading to better patient outcomes. The study will involve adult patients scheduled for elective non-cardiac surgeries where blood pressure monitoring is standard practice. Participants will be monitored using either continuous or intermittent methods to assess the impact on postoperative complications.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older scheduled for elective non-cardiac surgeries requiring non-invasive blood pressure monitoring.

Not a fit: Patients with chronic kidney disease, those requiring dialysis, or undergoing urological procedures may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risk of postoperative organ failure by improving blood pressure management during surgery.

How similar studies have performed: Previous studies have shown promise in using continuous non-invasive monitoring to improve patient outcomes, suggesting this approach may be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All adult (age ≥18 years) patients scheduled for elective non-cardiac surgery in participating centers
* Surgical case planned with non invasive blood pressure monitoring according to local clinical practice or policies.

Exclusion Criteria:

* Missing of preoperative serum creatinine during 30 days prior surgery
* Preoperative dialysis
* Chronic kidney disease (eGFR \< 60ml/min Cockcroft-Gault equation)
* Surgical procedure lasting less than 60 min
* Planned use of permissive hypotension
* Urological procedures (including nephrectomy and renal transplantation)
* Refusal to give informed consent

Where this trial is running

Messina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Blood Pressure DeterminationHemodynamic MonitoringPostoperative ComplicationsVolume clampContinuous non invasive blood pressure monitoring
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.