Comparing comfort of anesthesia-free tonometer tips for glaucoma testing

Tolerability of an Anesthesia-free Tonometer Tip

Not applicable Interventional Duke University · NCT06585423

This study is testing three new types of eye pressure measuring tools that don't need numbing to see which one feels the most comfortable for people with glaucoma.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorDuke University Academic / other
Locations1 site (Durham, North Carolina)
Trial IDNCT06585423 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the tolerability and comfort of three different prototype anesthesia-free tonometer tips compared to the standard tonometer tip that requires anesthesia. Participants will undergo routine eye exams where their responses to the different tonometer tips will be assessed. The goal is to identify the most comfortable prototype for further development, potentially leading to home tonometry options for glaucoma patients.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are presenting for a routine eye exam and can provide consent.

Not a fit: Patients with a history of corneal scarring, active eye infections, or previous corneal surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to a more comfortable and accessible method for glaucoma monitoring at home.

How similar studies have performed: While the specific approach of anesthesia-free tonometry is novel, similar studies have explored comfort in tonometry methods, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presenting for a routine eye exam
* ≥ 18 years of age
* Able and willing to give consent

Exclusion Criteria:

* History of corneal scarring
* Active infection of the eye
* History of alternated corneal sensitivity
* History of corneal surgery

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Glaucoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.