Comparing cold and hot snare techniques for removing large colorectal polyps
Official title: Cold Snare Endoscopic Mucosal Resection (C-EMR) Versus Hot Snare Endoscopic Mucosal Resection (H-EMR) for Large Colorectal Polyps (10-20 mm) - A Randomised Control Trail.
Run by Asian Institute of Gastroenterology, India · NCT06180798 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether using cold or hot snare techniques is better for safely removing large colorectal polyps in people who need this procedure.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 330 (estimated) |
| Sponsor | Asian Institute of Gastroenterology, India Academic / other |
| Locations | 1 site (Hyderabad, Telanagana) |
| Trial ID | NCT06180798 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with colorectal polyps measuring between 10-20 mm.
✕Probably not a fit
Patients with inflammatory bowel disease, familial polyposis syndromes, or severe coagulopathy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effectiveness of cold snare endoscopic mucosal resection (C-EMR) and hot snare endoscopic mucosal resection (H-EMR) for the removal of non-pedunculated colorectal polyps sized between 10-20 mm. A total of 330 participants will be randomly assigned to either intervention group, where experienced endoscopists will perform the procedures under sedation. The study will assess complete resection rates and any adverse events following the procedures, utilizing techniques such as saline and blue dye injection and narrow band imaging for inspection post-polypectomy.
Why it matters
Potential benefit: If successful, this study could lead to improved techniques for the safe and effective removal of large colorectal polyps, potentially reducing complications and improving patient outcomes.
How similar studies have gone: Previous studies have shown varying success with both cold and hot snare techniques, but this specific comparison is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult above 18 years * polyp size greater than 5-10mm. Exclusion Criteria: * Inflammatory bowel disease * Familial Polyposis Syndromes * Patient who is unable to understand study protocol or not consenting * Severe coagulopathy (INR Greater than 1.5 platelets) * Receiving antiplatelets withing 5 days of procedure * If antiplatelets stopped for 5 days-they were restarted on next day after procedure.
Where it's running
-
Krithi Krishna Koduri
Hyderabad, Telanagana, India Recruiting
Study contacts
- Principal investigator: Krithi Krishna Koduri, MD — Asian Institute of Gastroenterology
- Study coordinator: Krithi Krishna Koduri, MD
- Email: drkrithivk@gmail.com
- Phone: 9870083545
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.