Comparing Ciprofol and Propofol for Pain After Surgery
Comparative Effects of Ciprofol and Propofol on Pain Intensity of the Patients Without PCA on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study
This study is testing whether Ciprofol or Propofol works better to reduce pain for patients on the first day after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6500 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Guangdong Second Provincial General Hospital Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06020469 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effects of two anesthetic agents, Ciprofol and Propofol, on pain intensity experienced by patients on the first day after undergoing non-local anesthesia surgery. Utilizing a data intelligence platform that incorporates natural language processing and machine learning algorithms, the study seeks to analyze postoperative pain outcomes in a cohort of patients. The research will involve a retrospective analysis of patient data to identify differences in pain management effectiveness between the two anesthetics.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are scheduled for non-local anesthesia surgeries.
Not a fit: Patients undergoing day surgery, those with a history of multiple operations, or those who require ICU admission post-surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing surgery.
How similar studies have performed: While the use of machine learning and NLP in perioperative management is emerging, this specific comparative analysis of Ciprofol and Propofol is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients were included if they were above 18 years old, undergoing non-local anesthesia surgery. Exclusion Criteria: * The basic information such gender, age, height, weight, and body mass index (BMI) were missing. * Patients undergoing day surgery, with a history of multiple operations, or entering ICU after surgery, and losing the NRS score during movement at 24h after surgery.
Where this trial is running
Guangzhou, Guangdong
- Guangdong Second Provincial General Hospital — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Hui Zhang
- Email: zhanghui@gd2h.org.cn
- Phone: 13719136792
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.