Comparing Chitosan Brushes and Air-Abrasive Devices for Treating Peri-implant Mucositis

Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical

Not applicable Interventional Istanbul University · NCT06287957

This study is testing whether a chitosan brush or an air-abrasive device works better to treat gum problems around dental implants in patients with single implants and cemented crowns.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment54 (estimated)
SexAll
SponsorIstanbul University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Istanbul, Fatih)
Trial IDNCT06287957 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of two different cleaning methods for treating peri-implant mucositis in patients with single implants and cemented crowns. Participants will be randomly assigned to receive treatment with either a chitosan brush or an air-abrasive device, with their progress monitored over 12 weeks through measurements of bleeding, plaque index, and probing depth. The study aims to determine which method is more effective in reducing symptoms of peri-implant mucositis.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with peri-implant mucositis around at least one implant in the posterior region of the mouth.

Not a fit: Patients who are pregnant, have uncontrolled diabetes, or have a history of chemotherapy or radiotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment options for patients suffering from peri-implant mucositis, enhancing their oral health and comfort.

How similar studies have performed: While there have been studies on peri-implant mucositis treatments, the specific comparison of chitosan brushes and air-abrasive devices is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presence of peri-implant mucositis around at least one implant,
* Being over 18 years old,
* Being psychologically suitable,
* The teeth adjacent to the relevant implant are natural teeth,
* Having at least 1 implant in the maxillary or mandibular posterior region (teeth 4, 5, 6 and 7) and a cemented prosthesis that is not connected to other implants or teeth as its superstructure,
* Probing depth longer than 3 mm and shorter than 5 mm,
* Evidence of bleeding is required on probing.

Exclusion Criteria:

* Pregnancy
* History of chemotherapy and/or radiotherapy received in the past or currently being received,
* Bone loss around the implant,
* Presence of an implant in the area adjacent to the relevant implant,
* Dentures combined with other implants or teeth,
* Screw-retained prostheses
* Uncontrolled diabetes

Where this trial is running

Istanbul, Fatih

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Peri-implant MucositisPeri-ImplantitisBleeding on ProbingPeriodontal Pocketperi-implant mucositisLabrida BiocleanAir-flowChitosan Brush
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.