Comparing caries detection methods in children

A Clinical Study to Compare Caries Detection in Children Between the iTero Element 5D System (NIRI=Near Infra Red Imaging) and Bitewing Radiographs (BWR) as a Diagnostic Aid for the Detection of Primary Carious Lesions Above the Gingiva.

NA · Hadassah Medical Organization · NCT05792631

This study tests if a new dental imaging system can find cavities in children aged 4-9 better than traditional X-rays.

Quick facts

PhaseNA
Study typeInterventional
Enrollment70 (estimated)
Ages4 Years to 9 Years
SexAll
SponsorHadassah Medical Organization (other)
Locations1 site (Jerusalem)
Trial IDNCT05792631 on ClinicalTrials.gov

What this trial studies

This clinical study aims to evaluate the effectiveness of the iTero Element 5D system in detecting dental caries in children aged 4-9 years compared to traditional bitewing radiographs. Conducted at the Hadassah Medical Center in Israel, the study involves a single visit where participants will undergo both imaging methods. The results will be assessed according to established ADA staging guidelines, allowing for a direct comparison of the two diagnostic approaches. The study is designed to enhance understanding of caries detection in pediatric dentistry.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 4-9 years who are scheduled for routine bilateral bitewing radiographs.

Not a fit: Patients with a history of epilepsy or allergies to dental materials may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of caries detection in children, leading to better dental care outcomes.

How similar studies have performed: While similar studies have explored advanced imaging techniques, this specific comparison of the iTero Element 5D system with traditional methods is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ages 4-9 years
* Subjects scheduled for bilateral BWR as part of their standard of care
* Subjects with a recent bilateral BWR which were obtained up to 14 days prior to study visit

Exclusion Criteria:

* Subjects who have been diagnosed with epilepsy
* Subjects with a known allergy to latex or plastic
* Subjects with allergies to any dental or oral health products
* Subjects who have undergone a dental treatment since the acquisition of the recent bilateral BWR

Where this trial is running

Jerusalem

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Dental Caries, Patient Compliance

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.