Comparing Buddhist mindfulness training and secular cognitive therapy for depression

Comparing the Efficacy of Traditional Buddhist Mindfulness Training Versus Secular Mindfulness-based Cognitive Therapy for Residual Depressive Symptoms in Patients With Depressive Disorders: a Pilot Randomized Controlled Trial

NA · University of Kelaniya · NCT06456931

This study is testing whether traditional Buddhist mindfulness training or a modern therapy can help people with lingering depression feel better and improve their overall well-being.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Kelaniya (other)
Locations1 site (Ragama, Gampaha)
Trial IDNCT06456931 on ClinicalTrials.gov

What this trial studies

This pilot study aims to compare the effectiveness of traditional Buddhist mindfulness training with secular mindfulness-based cognitive therapy (MBCT) in patients experiencing residual depressive symptoms. The study will assess primary outcomes such as the reduction of depressive symptoms and improvement in psychological well-being, as well as secondary outcomes including self-compassion and spirituality. Conducted at Colombo North Teaching Hospital, the trial will involve 30 participants in each group undergoing 8 weeks of intervention followed by a 12-month follow-up to evaluate relapse prevention. Factors influencing the efficacy of these interventions will also be explored.

Who should consider this trial

Good fit: Ideal candidates for this study are Buddhist individuals aged 18 or older with a history of moderate to severe depression and currently experiencing mild to moderate depressive symptoms.

Not a fit: Patients with severe depressive episodes or significant suicidal ideation will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective therapeutic approaches for managing depression, potentially leading to improved treatment options.

How similar studies have performed: While mindfulness-based interventions have been studied extensively, this specific comparison of Buddhist mindfulness training and secular MBCT is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 or above
* Buddhist faith (Only Buddhists are selected as one of the interventions involves Buddhist teachings, and any recruited participant has a probability of being enrolled in the Buddhist mindfulness intervention)
* A history of one or more episodes of moderate or severe depression
* Currently having BDI-II score \> 13, i.e., mild to moderate depressive symptoms

Exclusion Criteria:

* Currently having a severe depressive episode, according to the Composite International Diagnostic Interview (CIDI) Sinhalese version
* Currently having moderate to severe suicidal ideation (according to CIDI)
* Recent changes in antidepressant medication
* Unable to understand and communicate in Sinhalese

Where this trial is running

Ragama, Gampaha

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Depression Moderate, Depression Mild, mindfulness, depression, religiosity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.