Comparing breathing, muscle, activity, and sleep measures in adults with COPD, PRISm, and healthy people

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational comparison will enroll three groups of adults over 40—those with PRISm, those with clinically stable COPD, and healthy controls—and measure respiratory muscle strength, peripheral muscle strength, oxygenation, arterial stiffness, physical activity, and sleep. Participants will be recruited at Hacettepe University and undergo spirometry to confirm group status along with standardized strength tests, oxygen saturation monitoring, arterial stiffness assessment, and activity/sleep monitoring or questionnaires. People with severe orthopedic, neurological, or cardiac disease or recent COPD exacerbations are excluded to protect safety and data consistency. The goal is to describe functional and cardiovascular differences between PRISm and COPD that could guide follow-up and care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

PRISm group inclusion criteria;

* Being \>40 years old,
* Being diagnosed with PRISm,
* Volunteering to participate in the study,
* Not having any orthopaedic or neurological problems that may prevent participation in the measurements,
* Co-operation with measurements

Inclusion criteria for the COPD group;

* Being \>40 years old,
* Being diagnosed with COPD,
* To be clinically stable,
* Volunteering to participate in the study.

Inclusion criteria for healthy individuals;

* Being \>40 years old,
* Volunteering to participate in the study,
* No known chronic health problems,
* To be able to co-operate with the measurements.

Exclusion Criteria:

PRISm group exclusion criteria;

* Being diagnosed with COPD,
* Severe orthopaedic, neurological and cardiac diseases
* Not volunteering to participate in the study

Exclusion criteria for COPD group;

* Severe orthopaedic, neurological and cardiac diseases,
* Being in COPD exacerbation period,
* Not volunteering to participate in the study.

Healthy individuals exclusion criteria;

* Having a known chronic disease,
* Not volunteering to participate in the study

Where it's running

• Hacettepe University
  Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ece Kumlu, M.Sc
• Email: eekumlu@gmail.com
• Phone: +90-312-305 2525 ext 178

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.