Comparing blood biomarkers for lung cancer diagnosis
A Retrospective Study to Compare Biomarker Expression of Exosomes Derived From Peripheral Blood and Primary Lung Cancer Drainage Pulmonary Blood in Lung Cancer Patients
This study is testing different blood markers to see if they can help diagnose lung cancer more easily and reliably than traditional tissue biopsies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Korea University Guro Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05587114 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare various biomarkers found in peripheral blood and pulmonary venous blood of patients diagnosed with lung cancer. By analyzing blood samples, the study seeks to identify less invasive and more repeatable diagnostic methods compared to traditional tissue biopsies. The focus is on evaluating cancer markers and exosome markers to improve early diagnosis and prognosis of lung cancer. The study will utilize frozen blood plasma samples collected from patients who have undergone surgery for lung cancer.
Who should consider this trial
Good fit: Ideal candidates for this study are Korean adults who have not received neoadjuvant therapy and have no prior cancer diagnoses.
Not a fit: Patients who have received neoadjuvant therapy or have been diagnosed with other cancers may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accessible and less invasive diagnostic methods for lung cancer, improving early detection and patient outcomes.
How similar studies have performed: Other studies have shown promise in using liquid biopsies for cancer diagnosis, indicating that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults with Korean nationality * Patients who did not receive neoadjuvant therapy before surgery * Patients not diagnosed with any other cancer before surgery * Patients who agreed to the consent form for a donation of human materials during surgery Exclusion Criteria: * Patients who do not meet the inclusion criteria
Where this trial is running
Seoul
- Korea University Guro Hospital — Seoul, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: Hyun Koo Kim, MD, PhD — Korea University Guro Hospital
- Study coordinator: Hyun Koo Kim, MD, PhD
- Email: kimhyunkoo@korea.ac.kr
- Phone: 82-2-2626-1185
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.