Comparing biological and synthetic meshes for breast reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This feasibility study involves 60 women undergoing immediate breast reconstruction after mastectomy for breast cancer. Participants will be randomly assigned to receive either biological or synthetic mesh to support breast implants, with follow-up for 6 months to assess comfort with the allocation process. The study aims to evaluate patient satisfaction, quality of life, complications, and costs over a longer period in future research. The goal is to better understand the long-term safety and acceptability of both types of meshes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Female age ≥ 18 Women undergoing mastectomy and immediate one-stage mesh assisted implant breast reconstruction as standard treatment

Exclusion Criteria:

Revision reconstruction surgery Delayed reconstruction surgery

Where it's running

• University Hospitals of Derby and Burton NHS Foundation Trust
  Derby, United Kingdom Recruiting
• Wycombe Hospital
  High Wycombe, United Kingdom Recruiting
• Castle Hill Hospital
  Hull, United Kingdom Recruiting
• University Hospitals of Leicester NHS Trust
  Leicester, United Kingdom Recruiting
• Nottingham City Hospital
  Nottingham, United Kingdom Recruiting

Study contacts

• Study coordinator: Amit Goyal, MS, MD, FRCS
• Email: amit.goyal@nhs.net
• Phone: 01332786958

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.