Clinical trial No longer in our active list Interventional Ages 18 and up

Comparing bilateral and unilateral neuromobilization for Carpal Tunnel Syndrome

Official title: Examining the Effects of Bilateral Neuromobilization in Patients with Carpal Tunnel Syndrome: Comparison Study with Unilateral Application

Run by Gazi University · NCT06554405 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests if treating both hands at the same time helps people with Carpal Tunnel Syndrome feel better compared to treating just the affected hand.

More Carpal Tunnel Syndrome trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment44 (estimated)
SponsorGazi University
Academic / other
Locations1 site (Ankara)
Trial IDNCT06554405 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18 and older diagnosed with Carpal Tunnel Syndrome without other upper extremity conditions.

Probably not a fit

Patients with a history of surgery or trauma in the affected upper extremity or those with uncontrolled systemic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of bilateral neuromobilization compared to unilateral neuromobilization in patients diagnosed with Carpal Tunnel Syndrome (CTS). CTS is a common condition caused by median nerve compression at the wrist, leading to symptoms such as numbness, tingling, and pain. The study aims to determine if treating both extremities simultaneously offers superior benefits over treating only the affected side. Participants will be monitored for improvements in symptoms and functionality as part of the intervention.

Why it matters

Potential benefit: If successful, this approach could lead to more effective treatment options for patients suffering from Carpal Tunnel Syndrome.

How similar studies have gone: While there have been studies on neuromobilization techniques, this specific comparison of bilateral versus unilateral approaches is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals diagnosed with CTS,
* Aged 18 and above,
* Without any other conditions in either upper extremity (such as trigger finger, osteoarthritis, tenosynovitis)

Exclusion Criteria:

* Individuals with a history of surgery, trauma, or fracture in the same upper extremity,
* Those who have received an injection for CTS in the last 3 months,
* Those with poor cooperation,
* Those participating in any other treatment program during the study,
* Those with a history of uncontrolled systemic diseases or systemic diseases involved in the etiology of CTS (such as diabetes, thyroid diseases, rheumatoid arthritis),
* Those who have used orthoses regularly and/or received physiotherapy in the last 3 months,
* Individuals with marked thenar atrophy requiring early surgical intervention

Where it's running

  • Gazi University Faculty of Health Sciences
    Ankara, Turkey
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Matrix Rhythm Therapy for Carpal Tunnel Syndrome

    This study tests whether adding Matrix Rhythm Therapy to standard care helps people with mild-to-moderate carpal tunnel syndrome improve symptoms, hand function, grip and pinch strength, and quality of life.

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  • Carpal tunnel release vs placebo surgery in Finland

    In this trial, people with carpal tunnel syndrome are randomly assigned to either standard carpal tunnel surgery or a pretend surgery to see if relief comes from the operation itself or from placebo effects.

    Recruiting at 2 sites Helsinki University Central Hospital · Helsinki and 1 other locations · NCT07614425

  • High-intensity laser therapy for carpal tunnel syndrome

    This trial will test whether high-intensity laser therapy helps adults 18–65 with mild-to-moderate carpal tunnel syndrome reduce pain and improve nerve function and hand strength compared with a sham procedure.

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  • Ultrasound-guided needle release plus dextrose (D5W) hydrodissection for carpal tunnel syndrome

    This trial tests whether combining ultrasound-guided partial release of the transverse carpal ligament with dextrose (D5W) hydrodissection provides better symptom relief for adults with carpal tunnel syndrome and at least moderate symptoms.

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  • A mix of vitamins to help recovery after carpal tunnel surgery

    This will test whether taking alpha-lipoic acid, vitamin E, and B vitamins helps adults recover better after carpal tunnel release surgery.

    Recruiting Hospital Universiti Sains Malaysia · Kubang Kerian, Kelantan · NCT07312123

  • Symptom spread and pain sensitivity in carpal tunnel syndrome

    This test looks at whether people with carpal tunnel syndrome whose symptoms spread beyond the usual finger area have higher central pain sensitivity, using a questionnaire and pressure pain testing.

    Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Usküdar · NCT07114913

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.