Comparing awake thoracic epidural anesthesia to general anesthesia for thoracotomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of awake thoracic epidural anesthesia (TEA) versus general anesthesia (GA) in patients undergoing thoracotomy. It aims to address the high incidence of chronic postsurgical pain by evaluating the management of acute postoperative pain through these two anesthesia methods. The study will include patients aged 18 to 75 who are classified as ASA II or III and scheduled for thoracotomy, while excluding those with contraindications to TEA or significant health issues. The goal is to determine if TEA can be a viable sole method for anesthesia in major thoracic procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 75 years old.
* Both genders.
* American Society of Anesthesiologists (ASA) physical status classification II or III.
* Scheduled for thoracotomy.

Exclusion Criteria:

* Difficult airway management,
* Hemodynamically unstable patients, obesity (body mass index \>30).
* Absolute contraindication to thoracic epidural anesthesia such as (patient refusal, allergy to local anesthetics, coagulopathy, active neurologic disorders, skin infection at insertion site, uncooperative patients, uncontrolled cough, and unfavorable anatomy for thoracic epidural).
* Neurological disorders: risk of seizure, unable to cooperate, intracranial mass or brain edema, extensive pleural adhesions or previous pulmonary resections, hypoxemia (PaO2 \<60) or hypercarbia (PaCO2 \>50)
* Poor cardiac function (ejection fraction less than 50%).
* Patients with bad pulmonary function tests.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed E Abdel Fattah, MD
• Email: mohamed-elsaid@cu.edu.eg
• Phone: 00201284475792

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.