Comparing automatic and manual monitoring of endotracheal tube cuff pressure in children

Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Patients: A Randomized Controlled Cross-Over Study

Not applicable Interventional Dr. Behcet Uz Children's Hospital · NCT06965400

This study is testing whether using an automatic system to monitor the pressure of breathing tubes in children on ventilators works better and is easier for nurses than doing it by hand.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages1 Month to 18 Years
SexAll
SponsorDr. Behcet Uz Children's Hospital Academic / other
Locations4 sites (Aydın and 3 other locations)
Trial IDNCT06965400 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of automatic cuff pressure monitoring using the IntelliCuff® system versus manual monitoring in pediatric intensive care patients requiring mechanical ventilation. It is a prospective, randomized controlled cross-over study involving patients aged 1 month to 18 years who are intubated and expected to need invasive ventilation for at least 48 hours. Each patient undergoes two 24-hour monitoring periods, one with automatic and one with manual monitoring, to assess cuff pressure deviations and nursing workload. The goal is to determine if automatic monitoring improves cuff pressure control and reduces complications.

Who should consider this trial

Good fit: Ideal candidates are pediatric patients aged 1 month to 18 years requiring invasive mechanical ventilation for at least 48 hours.

Not a fit: Patients with tracheostomy, known tracheal pathology, or those who are extubated within 48 hours may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved cuff pressure management, reducing complications and nursing workload in pediatric intensive care.

How similar studies have performed: While the approach of automatic cuff pressure monitoring is gaining interest, this specific comparison has not been widely tested, making it a novel investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged between 1 month and 18 years who were intubated with a cuffed endotracheal tube and expected to require invasive mechanical ventilation for at least 48 hours were eligible for inclusion

Exclusion Criteria:

* Patients with tracheostomy, known tracheal pathology, extubated within 48 hours, or those requiring frequent ventilator adjustments due to clinical instability were excluded.

Where this trial is running

Aydın and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cuff PressureMechanical VentilationPediatric Intensive CareCuff pressureAutomatic monitoringMechanical ventilation
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.