Comparing Adapted Physical Activity with Education for Patients with Neurocognitive Disorders

Adapted Physical Activity Education in Patients With Neurocognitive Disorder: Single-blind, Single-center Randomized Controlled Trial

Not applicable Interventional Centre Hospitalier Universitaire de Nice · NCT05866822

This study is testing whether adding education about physical activity to a workout program helps people with early-stage memory problems feel better and improve their overall quality of life more than just the workout program alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment34 (estimated)
Ages70 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Nice Academic / other
Locations1 site (Nice)
Trial IDNCT05866822 on ClinicalTrials.gov

What this trial studies

This study compares the effects of a program of Adapted Physical Activity (APA) alone versus APA combined with a Physical Activity Education program (PAE) in patients with mild or early major neurocognitive disorders. Participants will be randomly assigned to one of the two conditions and will undergo three evaluations: at the start of the study, after three months of intervention, and three months post-intervention. The researchers hypothesize that the combination of APA and PAE will lead to greater improvements in physical activity levels, cognitive function, and quality of life compared to APA alone.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with mild neurocognitive disorder or early major neurocognitive disorder.

Not a fit: Patients with moderate or severe neurocognitive disorders, significant depressive syndromes, or those who are already sufficiently active may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the physical and cognitive well-being of patients with neurocognitive disorders.

How similar studies have performed: While similar approaches have been explored, this specific combination of APA and PAE in neurocognitive disorders is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* mild neurocognitive disorder or early major neurocognitive disorder

Exclusion Criteria:

* Medical pathology involving the vital prognosis in the short term
* Major neurocognitive disorder at moderate stage and beyond (DSM 5) and/or MMSE \< 20
* Unbalanced depressive syndrom
* Contraindication to the practice of the exercises proposed during the study;
* Major hearing or visual impairment;
* Sufficiently active with regard to the daily recommendations described by the WHO

Where this trial is running

Nice

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neurocognitive Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.