Comparing acylcarnitine profiles in ICU survivors based on length of stay
Acylcarnitine Profile After Intensive Care
This study looks at the differences in certain blood markers between ICU survivors who stayed for a long time and those who had shorter stays to see how their recovery might be affected.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Liege Academic / other |
| Locations | 1 site (Liège) |
| Trial ID | NCT05115734 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the acylcarnitine profiles of critically ill patients who survived a prolonged stay in the ICU (7 days or more) with those who had shorter stays (2 days). The study will assess how these profiles evolve over time in the long-stay survivors, focusing on the acylcarnitine/carnitine ratio, which is an important biomarker of mitochondrial function. By analyzing serum acylcarnitine levels, the research seeks to understand the metabolic disturbances that may occur in critically ill patients post-ICU. This could provide insights into potential interventions for improving recovery outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients who have survived either a prolonged ICU stay of at least 7 days or a shorter stay of 2 days.
Not a fit: Patients who refuse participation or those who have not been admitted to the ICU may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of metabolic disturbances in ICU survivors, potentially improving their recovery and long-term health.
How similar studies have performed: While this study focuses on a specific acylcarnitine profile in ICU survivors, similar studies have shown that metabolic profiling can provide valuable insights into patient recovery, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Group short stayers: ICU length of stay of 2 days * Group long stayers: ICU length of stay of at least 7 days Exclusion criteria: patient refusal
Where this trial is running
Liège
- University Hospital of Liège — Liège, Belgium (Recruiting)
Study contacts
- Study coordinator: Anne-Françoise Rousseau, MD, PhD
- Email: afrousseau@chuliege.be
- Phone: +3243667495
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.