Clinical trial Recruiting at 1 site Interventional Ages 45 and up

Community health workers aim to reduce colorectal cancer and cardiovascular disease risk

Official title: Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk

Run by Columbia University · NCT05174286 · Data updated 2026-11-12

This study is testing a community health worker program to see if it can help African Americans lower their risk of colorectal cancer and heart disease by improving screening rates and healthy habits.

More Colorectal Cancer trials

Quick facts

Study typeInterventional
Ages45 Years and up
SexAll
Enrollment880 (estimated)
SponsorColumbia University
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedMarch 19, 2023
Main results expectedJune 30, 2026
Study endsAugust 31, 2026
Registry record updatedSeptember 16, 2025
Trial IDNCT05174286 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are English-speaking Black individuals aged 45 years and older who are not up-to-date with colorectal cancer screenings.

Probably not a fit

Patients who are non-English speaking or younger than 45 years may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on developing a culturally tailored community-based prevention model to reduce the risk of colorectal cancer (CRC) and cardiovascular disease (CVD) among African Americans. The intervention includes a Screening, Brief Intervention, and Referral to Treatment (SBIRT) approach for CRC screening, alongside a web-based lifestyle program called 'Alive!' to address CVD risk factors. The study will compare the effectiveness of this community health worker-led intervention against usual care and evaluate its impact on dietary habits and overall health metrics. The goal is to improve screening rates and health outcomes in a population that faces significant disparities in CRC incidence and mortality.

Why it matters

Potential benefit: If successful, this study could significantly improve colorectal cancer screening rates and reduce cardiovascular disease risk among African Americans.

How similar studies have gone: Other studies have shown success with community health worker-led interventions in improving health outcomes, making this approach promising yet still innovative in the context of colorectal cancer prevention.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. English-speaking
2. Aged 45 years and older
3. Not up-to-date with CRC
4. Working telephone
5. Can provide informed consent

Exclusion Criteria:

1. Non-English speaking
2. \<45 years old

Where it's running

  • Columbia University Irving Medical Center
    New York, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.