Community health workers aim to reduce colorectal cancer and cardiovascular disease risk
Official title: Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
Run by Columbia University · NCT05174286 · Data updated 2026-11-12
This study is testing a community health worker program to see if it can help African Americans lower their risk of colorectal cancer and heart disease by improving screening rates and healthy habits.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years and up |
| Sex | All |
| Enrollment | 880 (estimated) |
| Sponsor | Columbia University Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | March 19, 2023 |
| Main results expected | June 30, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | September 16, 2025 |
| Trial ID | NCT05174286 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are English-speaking Black individuals aged 45 years and older who are not up-to-date with colorectal cancer screenings.
✕Probably not a fit
Patients who are non-English speaking or younger than 45 years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on developing a culturally tailored community-based prevention model to reduce the risk of colorectal cancer (CRC) and cardiovascular disease (CVD) among African Americans. The intervention includes a Screening, Brief Intervention, and Referral to Treatment (SBIRT) approach for CRC screening, alongside a web-based lifestyle program called 'Alive!' to address CVD risk factors. The study will compare the effectiveness of this community health worker-led intervention against usual care and evaluate its impact on dietary habits and overall health metrics. The goal is to improve screening rates and health outcomes in a population that faces significant disparities in CRC incidence and mortality.
Why it matters
Potential benefit: If successful, this study could significantly improve colorectal cancer screening rates and reduce cardiovascular disease risk among African Americans.
How similar studies have gone: Other studies have shown success with community health worker-led interventions in improving health outcomes, making this approach promising yet still innovative in the context of colorectal cancer prevention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. English-speaking 2. Aged 45 years and older 3. Not up-to-date with CRC 4. Working telephone 5. Can provide informed consent Exclusion Criteria: 1. Non-English speaking 2. \<45 years old
Where it's running
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Columbia University Irving Medical Center
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Olajide A. Williams, MD, MS — Columbia University
- Study coordinator: Lisa Matthews, EdD, MPH
- Email: lam2160@cumc.columbia.edu
- Phone: 212-853-1150
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.