Community engagement strategies to improve HPV vaccination and screening in Nigeria
A Pragmatic Trial on Actions For Collaborative Community Engaged Strategies for HPV
NA · Washington University School of Medicine · NCT06728085
This study is testing a new way to boost HPV vaccinations and screenings for mothers and their daughters in Nigeria by involving the community in creating a tailored campaign.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 1224 (estimated) |
| Ages | 9 Years to 65 Years |
| Sex | Female |
| Sponsor | Washington University School of Medicine (other) |
| Locations | 1 site (Yaba, Lagos) |
| Trial ID | NCT06728085 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance HPV prevention efforts among mother-daughter pairs in Nigeria through a participatory crowdsourcing approach. It will develop a combined HPV vaccination and self-collection campaign tailored to local communities, utilizing input from community members. The effectiveness of this campaign will be evaluated using a hybrid effectiveness-implementation design, targeting girls aged 9-14 for vaccination and women aged 30-65 for screening. The study will involve 612 mother-daughter dyads across 18 local government areas, with community health workers facilitating the campaign and collecting data.
Who should consider this trial
Good fit: Ideal candidates for this study are unvaccinated girls aged 9-14 and their mothers or female caregivers aged 30-65 who reside in the designated local government areas in Nigeria.
Not a fit: Patients who have recently been vaccinated for HPV or screened for cervical cancer within the last five years will not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could significantly increase HPV vaccination rates among girls and promote screening among mothers, ultimately reducing cervical cancer incidence.
How similar studies have performed: Preliminary findings from earlier pilot studies suggest that crowdsourced interventions may effectively increase HPV vaccination and screening uptake, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female participants * Aged between 9 and 14 years old for girls/daughters * Aged between 30 and 65 years old for mothers (mothers defined as any female caregiver, including biological and surrogate mothers or close relatives who meet the eligibility criteria) * Residing and planning to reside in any of the 18 local government areas for the next 12 months and willing to participate * Girls must be unvaccinated for HPV. * Mother must have no recent (at least within 5 years cervical cancer screening) * Mothers or caregivers must own a mobile phone to follow up with both daughters and mothers. * Participants must agree to the informed consent in English before enrolling in the study. Exclusion Criteria: * Inability to comply with the study protocol * Recently vaccinated girls for HPV * Recently screened mothers for HPV within the last 5 years * Illness, cognitive impairment, or threatening behavior with acute risk to self or others * No informed consent or cell phone
Where this trial is running
Yaba, Lagos
- Nigerian Institute of Medical Research — Yaba, Lagos, Nigeria (RECRUITING)
Study contacts
- Principal investigator: Juliet Iwelunmor, PhD — Washington University School of Medicine
- Study coordinator: Juliet Iwelunmor, PhD
- Email: ijuliet@wustl.edu
- Phone: 2405280123
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: HPV, HPV Vaccination, HPV Screening