Community-based intervention to reduce tuberculosis among people who inject drugs in Vietnam
DRug Use & Infections in ViEtnam: TuBerculosis Control Towards Tuberculosis Elimination Among People Who Inject Drugs: Evaluation of a Community-based Intervention in Vietnam
This study is testing a new community program to help reduce tuberculosis among people who inject drugs in Hai Phong, Vietnam, by improving access to care and support.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 4000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | ANRS, Emerging Infectious Diseases Government |
| Locations | 2 sites (Haiphong and 1 other locations) |
| Trial ID | NCT05655702 on ClinicalTrials.gov |
What this trial studies
This research aims to implement a targeted, multi-component community-based intervention to decrease tuberculosis (TB) prevalence among people who inject drugs (PWID) in Hai Phong, Vietnam. The study will utilize repeated large-scale randomized driven sampling surveys to identify TB-infected PWID and assess their symptoms through questionnaires, CRP tests, chest X-rays, and sputum collection. The intervention is designed to enhance community involvement and improve access to TB care for this high-risk population, which has shown alarming TB prevalence rates. The study builds on previous findings that highlighted the significant TB burden among PWID in Vietnam.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older who self-declare as injecting heroin or other drugs and test positive for these substances.
Not a fit: Patients currently undergoing treatment for active TB or those with severe clinical conditions that may compromise their safety will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce TB prevalence among a vulnerable population, improving health outcomes and access to care.
How similar studies have performed: Other studies have shown success with community-based interventions targeting high-risk populations for TB, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Self-declaring injecting heroin or any other drug * Positive urine test for heroin or methamphetamine * Presence of recent injection site marks Exclusion Criteria: * Unable to understand or refused to sign informed consent * Patients currently under treatment for active TB * Any condition which might, in the investigator's opinion, compromise the safety of the patient by participating in the study, including very severe clinical condition * Person deprived of freedom by a judicial or administrative decision
Where this trial is running
Haiphong and 1 other locations
- Hai Phong University of Medecine and Pharmacy — Haiphong, Vietnam (Recruiting)
- Viettiep 2 Hospital — Haiphong, Vietnam (Recruiting)
Study contacts
- Principal investigator: Nicolas NAGOT — PCCI UMR 1058 - INSERM, Univ Montpellier, EFS, Montpellier, Franc
- Study coordinator: Marion BONNETON
- Email: marion.bonneton@inserm.fr
- Phone: +84344755013
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.