Community-based cognitive remediation program for schizophrenia and schizoaffective disorder
Official title: Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE): a Community-Based Cognitive Remediation Trial
Run by Singapore Institute of Technology · NCT06286202 · Data updated 2026-11-12
This study tests a community program that helps adults with schizophrenia and schizoaffective disorder improve their thinking skills through exercises and group support to see if it makes their daily lives better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 60 Years |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Singapore Institute of Technology Academic / other |
| Locations | 5 sites (Singapore and 4 other locations) |
| Status | Recruiting |
| Started | August 6, 2024 |
| Main results expected | June 2027 |
| Study ends | December 2027 |
| Registry record updated | January 27, 2026 |
| Trial ID | NCT06286202 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults diagnosed with schizophrenia or schizoaffective disorder who have completed at least ten years of formal education and can converse in English.
✕Probably not a fit
Patients with neurological diseases, those unable to understand English, or those with very low functioning may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This program aims to improve cognitive skills in adults with schizophrenia and schizoaffective disorders through a community-based cognitive remediation approach. Participants will engage in a structured intervention that includes computer-assisted exercises and group sessions facilitated by therapists. The study will also explore how motivation and social interaction influence cognitive improvements and functional abilities. The focus is on addressing cognitive impairments that hinder community integration and quality of life.
Why it matters
Potential benefit: If successful, this program could enhance cognitive functioning and improve the quality of life for patients with severe mental illnesses.
How similar studies have gone: Previous studies have shown positive outcomes with cognitive remediation approaches, suggesting potential for success in this community-based setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * A diagnosis of schizophrenia or schizoaffective disorder according to Diagnostic and Statistical Manual of Mental Disorders-5th Edition (DSM-V). * Completed at least ten years of formal education with English as the main instructional language. Participants need to be able to converse in English and understand English instructions, as the cognitive remediation program will be conducted in English. Exclusion Criteria: * Known neurological diseases and epilepsy, which affects gains from cognitive remediation. * Unable to speak and understand English. * Hospitalized within the past one month. * Global Assessment of Functioning score of 30 or below, as participants who are too low functioning are unable to benefit from a strategy learning approach.
Where it's running
-
Anglican Care Center-Bukit Batok
Singapore, Singapore Recruiting -
Anglican Care Center-Hougang
Singapore, Singapore Recruiting -
Anglican Care Center-Simei
Singapore, Singapore Recruiting -
Anglican Care Center-Pasir Ris
Singapore, Singapore Not yet recruiting -
Anglican Care Center-Yishun
Singapore, Singapore Not yet recruiting
Study contacts
- Principal investigator: Bhing-Leet Tan, PhD — Bhing-Leet Tan
- Study coordinator: Bhing-Leet Tan, PhD
- Email: bhingleet.tan@singaporetech.edu.sg
- Phone: +6598422783
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.