Combining ultrasound-guided hyaluronic acid injections, high-power laser therapy, and rehabilitation for hip osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind controlled trial enrolled 57 adults with Kellgren-Lawrence stage 1–3 hip osteoarthritis, pain ≥4/10, and BMI <30 at the University Magna Graecia of Catanzaro. Participants were randomly assigned to receive ultrasound-guided hyaluronic acid injections plus active high-power laser therapy and rehabilitation, or the same care with a sham laser intervention. The primary outcome was the Harris Hip Score, with secondary outcomes including the Numeric Rating Scale for pain, EQ-5D quality-of-life, and the 6-minute walk test, measured at baseline, post-treatment, and at 3, 6, and 12 months. Blinding of patients and assessors and repeated follow-up allowed comparison of function, pain, and physical performance over one year.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age over 18 years
* Diagnosis of hip OA (stage ≤ 3 according to the Kellgren and Lawrence classification)
* Hip pain assessed with the Numeric Rating Scale ≥ 4
* Body mass index (BMI) less than 30 kg/m²
* Suspension of anti-inflammatory drugs (NSAIDs), opioids, corticosteroids, muscle relaxants or any other therapy that could interfere with the study assessments.

Exclusion Criteria:

* Mini-Mental State Examination (MMSE) score \< 24
* Concurrent treatment with an-ti-inflammatory drugs or rehabilitation therapies; Rheumatoid arthritis.

Where it's running

• University "Magna Graecia "of Catanzaro
  Catanzaro, Cz, Italy Recruiting
• University "Magna Graecia "of Catanzaro
  Catanzaro, Italy Recruiting

Study contacts

• Study coordinator: Professor Alessandro de Sire
• Email: alessandro.desire@unicz.it
• Phone: +393297219090

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.