Combining ultrasonic cleaning and a 980 nm diode laser to reduce pain and bacteria after root canal treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a parallel randomized controlled trial following PRIRATE 2020 guidelines that enrolls adults (20–35 years) with single‑rooted necrotic teeth and periapical radiolucencies up to 5 mm. Participants are randomized into treatment groups receiving conventional irrigation, ultrasonic activation, 980 nm diode laser, or the combination of ultrasonic activation with the diode laser. The trial measures postoperative pain as the primary clinical outcome and quantifies antibacterial effect by bacterial sampling. Ethical approval and informed consent procedures were completed at the Faculty of Dental Medicine for Girls, Al‑Azhar University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients have mature teeth with closed apex.
* Single-rooted teeth with root canal form type I.
* Asymptomatic.
* Have periapical radiolucency with a diameter of up to 5 mm.
* Restorable teeth.

Exclusion Criteria:

* Patients with symptomatic apical periodontitis.
* Systemic disease.
* Physical or mental disability.
* Root fracture and tooth mobility.

Where it's running

• from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Sabah M. Sobhy, PHD — Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egyp
• Study coordinator: Sabah M. Sobhy, PHD
• Email: sabamorad@yahoo.com
• Phone: +201096529143

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.