Combining statins with amlodipine to treat primary aldosteronism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of combining statins with amlodipine in treating patients with primary aldosteronism. Participants will be randomly assigned to one of three treatment groups: one receiving statin and amlodipine, another receiving statin, spironolactone, and amlodipine, and the last receiving amlodipine and spironolactone. The study will monitor changes in plasma aldosterone levels, 24-hour urinary aldosterone, blood pressure, and long-term cardiovascular risks associated with these treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of primary aldosteronism

Exclusion Criteria:

* Allergy to drugs in this study
* Pregnancy
* Severe liver and kidney dysfunction
* Mental illness

Where it's running

• No. 10 Changjiang River Branch, Yuzhong District，Chongqing, China
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Study coordinator: sun fang
• Email: sun_fang2007@163.com
• Phone: +862368729587

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Impact of Aldosterone Blockade on Heart Function in Primary Aldosteronism

  This study is testing if a medication that blocks a hormone called aldosterone can improve heart function in people with primary aldosteronism, which causes high blood pressure.

  Recruiting Phase 4 Brigham and Women's Hospital · Boston, Massachusetts · NCT05030545

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.