Combining resistance exercise with creatine for colorectal cancer survivors
The Feasibility and Acceptability of Resistance Training and Creatine Supplementation to Promote Physical Function in Sarcopenic Colorectal Cancer Survivors
This study is testing if combining creatine supplements with resistance exercise can help colorectal cancer survivors build muscle and feel stronger after treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of South Carolina Academic / other |
| Locations | 1 site (Columbia, South Carolina) |
| Trial ID | NCT06420726 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility of combining creatine supplementation with resistance training to combat sarcopenia in colorectal cancer survivors. Sarcopenia, characterized by loss of muscle mass and function, affects a significant portion of this population due to various factors including treatment side effects and malnutrition. Participants will be randomly assigned to either a 10-week program of resistance exercise plus creatine or resistance exercise alone. The goal is to assess the acceptability and effectiveness of this combined approach in improving muscle health post-cancer treatment.
Who should consider this trial
Good fit: Ideal candidates are individuals over 18 years who are at least 12 months post-treatment for colorectal cancer and are experiencing sarcopenia.
Not a fit: Patients currently undergoing active cancer treatment or those with contraindications to exercise will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve muscle mass and function in colorectal cancer survivors, enhancing their quality of life.
How similar studies have performed: Previous studies have shown that combining creatine with resistance training can enhance muscle mass and function in various populations, suggesting potential success for this approach in colorectal cancer survivors.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * . Individuals ≥12 months post treatment for colorectal cancer * \>18 years Exclusion Criteria: 1. are receiving active treatment for their cancer; 2. have a any contraindication to exercise participation; 3. have been participating in structured resistance exercise 2 or more times per week for the past 6 months; 4. are currently taking supplements containing creatine for 4 weeks prior to the start of the RCT, or 5. are receiving medications that might alter body composition (metformin, corticosteroids etc.).
Where this trial is running
Columbia, South Carolina
- University of South Carolina — Columbia, South Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Ciaran Fairman, PhD — University of South Carolina
- Study coordinator: Ciaran Fairman
- Email: cfairman@mailbox.sc.edu
- Phone: 803-576-8397
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.