Combining 40Hz light therapy with cognitive training for Alzheimer's treatment
Official title: An Observational Trial of Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
Run by Alzheimer's Light LLC · NCT03657745 · Data updated 2026-11-12
This study is testing whether using a special iPad app that combines 40Hz light therapy with brain exercises can help improve thinking and daily life for people with Alzheimer's disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Alzheimer's Light LLC Industry-sponsored |
| Locations | 1 site (Miami, Florida) |
| Status | Recruiting |
| Started | January 1, 2018 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | August 1, 2024 |
| Trial ID | NCT03657745 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with Alzheimer's disease or mild cognitive impairment.
✕Probably not a fit
Patients with a history of epileptic seizures or significant eye diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of a novel iPad app that delivers 40Hz light therapy combined with cognitive therapy on patients with Alzheimer's disease and cognitive impairment. The approach is based on recent findings that exposure to flickering light can enhance gamma brainwave activity, potentially aiding in the clearance of beta amyloid plaques associated with Alzheimer's. Participants will engage in daily sessions of light therapy and cognitive exercises to assess improvements in cognition, function, and overall quality of life. The study aims to evaluate the effectiveness of this combined intervention in a real-world setting.
Why it matters
Potential benefit: If successful, this approach could significantly improve cognitive function and quality of life for patients with Alzheimer's disease.
How similar studies have gone: Previous studies have shown promising results with similar light therapy approaches, indicating potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Alzheimer's disease * Cognitive Impairment Exclusion Criteria: * any previously noted epileptic seizures, including febrile seizures. * any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.
Where it's running
-
Andrey Vyshedskiy
Miami, Florida, United States Recruiting
Study contacts
- Study coordinator: Andrey Vyshedskiy, Ph.D.
- Email: vysha@bu.edu
- Phone: (617) 433-7724
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.