Combined high-intensity interval and resistance training for obese men with high blood pressure

Effects of Combined High Intensity Interval Training and Resistance Training on Body Composition, Blood Pressure, and Cardiorespiratory Fitness in Obese Hypertensive Men

Not applicable Interventional Prince Sattam Bin Abdulaziz University · NCT06845436

This trial will test whether combining high-intensity interval training with resistance training can improve blood pressure, body composition, and fitness in obese men aged 40–60 with hypertension.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages40 Years to 60 Years
SexMale
SponsorPrince Sattam Bin Abdulaziz University Academic / other
Locations1 site (Riyadh, Alkharj)
Trial IDNCT06845436 on ClinicalTrials.gov

What this trial studies

Sixty obese, physically inactive men aged 40–60 with stage 1 or 2 hypertension will be assigned to one of three groups: combined HIIT plus resistance training, HIIT alone, or a control group. The combined group will complete three weekly sessions of both HIIT and resistance training for 16 weeks; HIIT sessions involve four 4-minute high-intensity intervals at 80–95% of HRmax interspersed with 2-minute active recovery intervals at 40–60% HRmax, and resistance sessions comprise eight exercises. Outcomes measured before and after the intervention include body composition, resting blood pressure, and cardiorespiratory fitness. Participants with diabetes, chronic respiratory or heart disease, or musculoskeletal limitations are excluded.

Who should consider this trial

Good fit: Men aged 40–60 who are obese (BMI > 30), diagnosed with stage 1 or 2 hypertension, and currently physically inactive would be ideal candidates.

Not a fit: People with diabetes, chronic heart or respiratory disease, or musculoskeletal problems preventing exercise are unlikely to benefit from or be eligible for this intervention.

Why it matters

Potential benefit: If successful, the program could lower blood pressure and improve body composition and fitness in obese hypertensive men.

How similar studies have performed: Prior research shows aerobic and resistance exercise can lower blood pressure and improve fitness, and combining HIIT with resistance training is a plausible but less-studied approach with promising preliminary results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* men aged between 40 and 60 years old,
* have been diagnosed with clinical stage 1 or 2 hypertension,
* being obese with body mass index more than 30 kg/m2
* physically inactive

Exclusion Criteria:

* musculoskeletal problems that may limit their ability to participate in resistance or HIIT programs
* diabetes mellitus
* a history of respiratory or chronic heart disease

Where this trial is running

Riyadh, Alkharj

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertensionhypertension.obesityHigh Intensity Interval Trainingresistance trainingblood pressure
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.