Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Colonoscopy for colorectal cancer screening using hypnosis

Official title: Colorectal Cancer Screnning Colonoscopy Under Hypnosis: A Multicenter Randomized Non-Inferiority Trial

Run by University Hospital, Tours · NCT05051046 · Data updated 2026-11-12

This study tests if using hypnosis instead of general anesthesia during colonoscopy can help people feel less anxious and uncomfortable while getting screened for colorectal cancer.

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment600 (estimated)
SponsorUniversity Hospital, Tours
Academic / other
Locations1 site (Angers)
StatusRecruiting
StartedJanuary 31, 2022
Main results expectedFebruary 7, 2028
Study endsFebruary 7, 2028
Registry record updatedNovember 24, 2025
Trial IDNCT05051046 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older who are undergoing a screening colonoscopy and are affiliated with the French social security system.

Probably not a fit

Patients requiring emergency colonoscopy or those with contraindications to hypnosis or general anesthesia may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of hypnosis as an alternative to general anesthesia during colonoscopy for colorectal cancer screening. Colorectal cancer is a prevalent condition, and colonoscopy is a critical screening tool that is often performed under general anesthesia due to patient discomfort. The study aims to determine if hypnosis can reduce anxiety and pain, making the procedure more acceptable to patients while also minimizing the risks and costs associated with general anesthesia. By assessing patient tolerance and outcomes, the study seeks to provide a viable option for those undergoing screening.

Why it matters

Potential benefit: If successful, this approach could lead to safer and more cost-effective colorectal cancer screenings for patients.

How similar studies have gone: While hypnosis has been tested in various contexts, most studies have been small and non-randomized, making this approach relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients 18 years of age or older
* Undergoing a screening colonoscopy (mass screening Fecal Immunochemical Test positive or as an individual (family history of colon cancer or adenoma, personal history of adenoma, cancer, chronic inflammatory bowel disease) or in the context of a transit disorder, hemorrhage or anemia
* Affiliated with a French social security system
* Having signed a written consent

Exclusion Criteria:

* Patient requiring emergency colonoscopy
* History of colonic resection
* Carriers of behavioral disorders and/or psychiatric illness
* Limited cognitive abilities making it impossible to read or fill out a discrete choice questionnaire (language problems, comprehension problems)
* Contraindication to hypnosis, preventing quality interaction (comprehension and/or language problems, hearing impairment)
* Contraindication to general anesthesia
* Under a legal protection regime
* Pregnant or breastfeeding woman

Where it's running

  • Chu Angers
    Angers, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.