Colonoscopy for colorectal cancer screening using hypnosis
Official title: Colorectal Cancer Screnning Colonoscopy Under Hypnosis: A Multicenter Randomized Non-Inferiority Trial
Run by University Hospital, Tours · NCT05051046 · Data updated 2026-11-12
This study tests if using hypnosis instead of general anesthesia during colonoscopy can help people feel less anxious and uncomfortable while getting screened for colorectal cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | University Hospital, Tours Academic / other |
| Locations | 1 site (Angers) |
| Status | Recruiting |
| Started | January 31, 2022 |
| Main results expected | February 7, 2028 |
| Study ends | February 7, 2028 |
| Registry record updated | November 24, 2025 |
| Trial ID | NCT05051046 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who are undergoing a screening colonoscopy and are affiliated with the French social security system.
✕Probably not a fit
Patients requiring emergency colonoscopy or those with contraindications to hypnosis or general anesthesia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of hypnosis as an alternative to general anesthesia during colonoscopy for colorectal cancer screening. Colorectal cancer is a prevalent condition, and colonoscopy is a critical screening tool that is often performed under general anesthesia due to patient discomfort. The study aims to determine if hypnosis can reduce anxiety and pain, making the procedure more acceptable to patients while also minimizing the risks and costs associated with general anesthesia. By assessing patient tolerance and outcomes, the study seeks to provide a viable option for those undergoing screening.
Why it matters
Potential benefit: If successful, this approach could lead to safer and more cost-effective colorectal cancer screenings for patients.
How similar studies have gone: While hypnosis has been tested in various contexts, most studies have been small and non-randomized, making this approach relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 18 years of age or older * Undergoing a screening colonoscopy (mass screening Fecal Immunochemical Test positive or as an individual (family history of colon cancer or adenoma, personal history of adenoma, cancer, chronic inflammatory bowel disease) or in the context of a transit disorder, hemorrhage or anemia * Affiliated with a French social security system * Having signed a written consent Exclusion Criteria: * Patient requiring emergency colonoscopy * History of colonic resection * Carriers of behavioral disorders and/or psychiatric illness * Limited cognitive abilities making it impossible to read or fill out a discrete choice questionnaire (language problems, comprehension problems) * Contraindication to hypnosis, preventing quality interaction (comprehension and/or language problems, hearing impairment) * Contraindication to general anesthesia * Under a legal protection regime * Pregnant or breastfeeding woman
Where it's running
-
Chu Angers
Angers, France Recruiting
Study contacts
- Principal investigator: Driffa MOUSSATA, PhD — University Hospital Center of Tours
- Study coordinator: Driffa MOUSSATA, PhD
- Email: D.MOUSSATA@chu-tours.fr
- Phone: +33 2 47 47 83 50
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.