Collection of synovial fluid from arthritis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to collect synovial fluid and paired serum samples from patients with arthritis to evaluate novel biomarkers related to joint damage and inflammation. The study will focus on understanding the prevalence and diagnostic/prognostic values of these biomarkers, as well as how therapeutic interventions may influence their levels. Specific attention will be given to biomarkers associated with bone resorption, cartilage degradation, and the activity of proteases involved in joint damage. The findings could lead to the identification of new therapeutic targets for arthritis treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Significant joint effusion

Exclusion Criteria:

* Hemorrhagic effusion
* Traumatic effusion
* Less than 3 ml total of collected fluid (used for routine analysis and culture)
* Inability or refusal to consent

Where it's running

• Centre hospitalier universitaire de Sherbrooke
  Sherbrooke, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Gilles Boire, MD, MSc — CHUS and Université de Sherbrooke
• Study coordinator: Gilles Boire, MD, MSc
• Email: Gilles.Boire@USherbrooke.ca
• Phone: (819) 564-5261

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.