Collection of biological samples from patients with pelvic gynecological cancer and endometriosis
Official title: Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization
Run by Centre Hospitalier Intercommunal Creteil · NCT03622983 · Data updated 2026-11-12
This study is collecting samples from patients with pelvic gynecological cancers and endometriosis to see if they can find clues that help predict cancer recurrence and improve personalized treatments.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 500 (estimated) |
| Sponsor | Centre Hospitalier Intercommunal Creteil Academic / other |
| Locations | 2 sites (Créteil and 1 other locations) |
| Status | Recruiting |
| Started | May 1, 2017 |
| Main results expected | August 2027 |
| Study ends | August 2037 |
| Registry record updated | December 21, 2022 |
| Trial ID | NCT03622983 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with a diagnosis of pelvic gynecological cancer or endometriosis.
✕Probably not a fit
Patients who refuse to participate or are not affiliated with the general social security scheme may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to collect biological samples and detailed clinical data from patients diagnosed with pelvic gynecological cancers and endometriosis. By analyzing these samples, researchers hope to identify factors that predict cancer recurrence and develop personalized treatment strategies based on the biological characteristics of the tumors. The study focuses on the evolving biology of pelvic cancers and the potential for personalized medicine, particularly in relation to anti-PARP therapy for ovarian cancer. The findings could enhance understanding and management of these conditions.
Why it matters
Potential benefit: If successful, this study could lead to more effective, personalized treatment options for patients with pelvic gynecological cancers and endometriosis.
How similar studies have gone: Other studies have shown promising results in identifying predictive factors for recurrence in similar conditions, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of pelvic gynecological cancer posed on initial histological analysis or during recurrence; * Or diagnosis of endometriosis on histology or imaging * Age ≥ 18 years; * Affiliation to the general social security scheme; * Consent signed. Exclusion Criteria: * Refusal of the patient; * Non-affiliation to the general social security scheme.
Where it's running
-
CHI Creteil
Créteil, France Recruiting -
CHU Tenon
Paris, France Recruiting
Study contacts
- Study coordinator: Cyril Touboul
- Email: cyril.touboul@gmail.com
- Phone: 0156017000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparing different techniques to treat endometriosis
This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.
-
Postoperative Pain Trajectories After Endometriosis Surgery
This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.
-
Imaging endometriosis with a special PET tracer in adult women
This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.
-
Fiber supplement for digestive symptoms in endometriosis
A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.
-
Stellate ganglion block and dexmedetomidine for better sleep after gynecologic laparoscopy
The study tests whether giving a preoperative stellate ganglion block plus intraoperative dexmedetomidine improves sleep after laparoscopic gynecologic surgery in women.
-
Atypical Endometriosis: Histology, Immunophenotype and Molecular Features
Researchers will look at how endometriotic tissue that looks atypical under the microscope relates to clinical features and ultrasound findings to better separate benign from potentially atypical lesions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.