Collecting data on colorectal cancer patients
Prospective Data Collection Initiative on Colorectal Cancer - a Prospective Observational Cohort Study -
This study is collecting information from patients with colorectal, small bowel, and anal cancer to understand their treatment experiences and improve future care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Dutch Colorectal Cancer Group Academic / other |
| Locations | 67 sites ('s-Hertogenbosch and 66 other locations) |
| Trial ID | NCT02070146 on ClinicalTrials.gov |
What this trial studies
This observational cohort initiative aims to gather extensive data on patients diagnosed with colorectal, small bowel, and anal cancer from their initial diagnosis until death. It will collect information on medical history, treatment outcomes, and patient-reported outcomes, as well as biological samples for future research. The goal is to better understand the factors influencing treatment outcomes and to create a robust infrastructure for evaluating new interventions in a real-world setting.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with a confirmed diagnosis of colorectal, small bowel, or anal cancer.
Not a fit: Patients who are mentally incompetent or unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could lead to improved understanding of colorectal cancer outcomes and more personalized treatment approaches for patients.
How similar studies have performed: Other studies utilizing observational cohort designs have shown success in enhancing understanding of cancer treatment outcomes, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Histological proof of colorectal, small bowel and anal cancer, or a strong suspicion after imaging. * Informed consent for longitudinal observational data collection. Exclusion Criteria: * Mentally incompetent patients. Participation of patients to the PLCRC project does not exclude participation in any other ongoing or future study.
Where this trial is running
's-Hertogenbosch and 66 other locations
- Jeroen Bosch Ziekenhuis — 's-Hertogenbosch, Netherlands (Recruiting)
- Noordwest Ziekenhuisgroep — Alkmaar, Netherlands (Recruiting)
- Flevoziekenhuis — Almere Stad, Netherlands (Recruiting)
- Meander Medisch Centrum — Amersfoort, Netherlands (Recruiting)
- Ziekenhuis Amstelland — Amstelveen, Netherlands (Recruiting)
- Antoni van Leeuwenhoek — Amsterdam, Netherlands (Recruiting)
- Olvg — Amsterdam, Netherlands (Recruiting)
- VUmc — Amsterdam, Netherlands (Recruiting)
- Gelre Ziekenhuizen — Apeldoorn, Netherlands (Recruiting)
- Rijnstate — Arnhem, Netherlands (Recruiting)
- Wilhelmina Ziekenhuis Assen — Assen, Netherlands (Recruiting)
- Maasziekenhuis Pantein — Beugen, Netherlands (Recruiting)
- Rode Kruis Ziekenhuis — Beverwijk, Netherlands (Recruiting)
- Amphia ziekenhuis — Breda, Netherlands (Recruiting)
- IJsselland Ziekenhuis — Capelle aan den IJssel, Netherlands (Recruiting)
- Reinier de Graaf — Delft, Netherlands (Recruiting)
- Deventer Ziekenhuizen — Deventer, Netherlands (Recruiting)
- Van Weel-Bethesda Ziekenhuis — Dirksland, Netherlands (Recruiting)
- Slingeland Ziekenhuis — Doetinchem, Netherlands (Recruiting)
- Albert Schweitzer Ziekenhuis — Dordrecht, Netherlands (Recruiting)
- Ziekenhuis Gelderse Vallei — Ede, Netherlands (Recruiting)
- Catharina Ziekenhuis — Eindhoven, Netherlands (Recruiting)
- Maxima Medisch Centrum — Eindhoven, Netherlands (Recruiting)
- Medisch Spectrum Twente — Enschede, Netherlands (Recruiting)
- Anna Ziekenhuis — Geldrop, Netherlands (Recruiting)
- Admiraal De Ruyter Ziekenhuis — Goes, Netherlands (Recruiting)
- Rivas Beaterix Ziekenhuis — Gorinchem, Netherlands (Recruiting)
- Groene Hart Ziekenhuis — Gouda, Netherlands (Recruiting)
- Martini Ziekenhuis — Groningen, Netherlands (Recruiting)
- UMC Groningen — Groningen, Netherlands (Recruiting)
- Spaarne Gasthuis — Haarlem, Netherlands (Recruiting)
- Saxenburgh Groep — Hardenberg, Netherlands (Recruiting)
- St.Jansdal — Harderwijk, Netherlands (Recruiting)
- Frisius MC Heerenveen — Heerenveen, Netherlands (Recruiting)
- Elkerliek Ziekenhuis — Helmond, Netherlands (Recruiting)
- Ziekenhuisgroep Twente — Hengelo, Netherlands (Recruiting)
- Tergooi — Hilversum, Netherlands (Recruiting)
- Treant Zorggroep — Hoogeveen, Netherlands (Recruiting)
- Dijklander Ziekenhuis — Hoorn, Netherlands (Recruiting)
- Frisius MC Leeuwarden — Leeuwarden, Netherlands (Recruiting)
- Alrijne — Leiden, Netherlands (Recruiting)
- Leids Universitair Medisch Centrum — Leiden, Netherlands (Recruiting)
- Maastricht UMC+ — Maastricht, Netherlands (Recruiting)
- Maastro — Maastricht, Netherlands (Recruiting)
- St. Antonius ziekenhuis — Nieuwegein, Netherlands (Recruiting)
- Canisius Wilhelmina Ziekenhuis — Nijmegen, Netherlands (Recruiting)
- Radboud UMC — Nijmegen, Netherlands (Recruiting)
- Bernhoven — Oss, Netherlands (Recruiting)
- Laurentius Ziekenhuis — Roermond, Netherlands (Recruiting)
- Bravis ziekenhuis — Roosendaal, Netherlands (Recruiting)
+17 more sites — see ClinicalTrials.gov for the full list.
Study contacts
- Principal investigator: Miriam Koopman, MD, PhD — UMC Utrecht
- Study coordinator: Miriam Koopman, MD, PhD
- Email: m.koopman-6@umcutrecht.nl
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.