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Collecting data and specimens from pediatric cancer patients

Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers

Observational Milton S. Hershey Medical Center · NCT04715178

This study is collecting samples and information from kids with cancer to see how their genes and tumor details can help find better treatments.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
SexAll
SponsorMilton S. Hershey Medical Center Academic / other
Locations18 sites (Little Rock, Arkansas and 17 other locations)
Trial IDNCT04715178 on ClinicalTrials.gov

What this trial studies

This observational registry study involves pediatric cancer patients at various sites within the Beat Childhood Cancer Consortium. It focuses on collecting specimens and data to explore the relationship between genomic and molecular information and clinical outcomes. The study aims to utilize large gene panels, sequencing, and epigenetics to identify molecular abnormalities in tumors, which could lead to more effective treatment options. The findings may prompt further research into the molecular aspects of pediatric cancers, supported by the creation of tumor cell lines and xenograft models.

Who should consider this trial

Good fit: Ideal candidates include pediatric patients with suspected or confirmed tumors who consent to participate in specimen banking and data collection.

Not a fit: Patients who do not consent to specimen banking and data collection will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for pediatric cancer patients.

How similar studies have performed: Other studies utilizing genomic and molecular data in pediatric cancer have shown promise, indicating that this approach is both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* No age restrictions
* Subjects that fit into one of the following categories:

  1. Subjects with suspected or confirmed cancers of childhood, adolescence, or young adulthood.
  2. Survivors of a cancer of childhood, adolescence, or young adulthood (\> 6 months off last therapy for cancer)
  3. Subjects with a disease-matched condition
  4. Healthy volunteers- including any participants with medical conditions that are not disease-matched.
* Written informed consent in accordance with institutional and FDA guidelines must be obtained from all subjects (or subjects' legal representative).

Exclusion Criteria:

* Subject or his/her legally authorized representative (where applicable) did not consent for specimen banking and data collection for this study.

Where this trial is running

Little Rock, Arkansas and 17 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Pediatric CancerSurvivorship
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.