Collecting cerebrospinal fluid to find new biomarkers for Alzheimer's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect cerebrospinal fluid samples from patients undergoing lumbar puncture as part of their dementia diagnosis. The goal is to identify and validate new biomarkers that could improve the diagnosis, prognosis, and treatment monitoring of Alzheimer's disease and other neurodegenerative conditions. By analyzing these samples, researchers hope to enhance the understanding of Alzheimer's pathology and develop more effective diagnostic tools.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Lumbar punction collected in usual practice in the context of dementia diagnosis

Exclusion Criteria:

* Absence of consent

Where it's running

• CHRU De Nancy
  Nancy, Grand Est, France Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hyperspectral retinal imaging to detect Alzheimer’s and other neurodegenerative changes

  This project will test whether a special retinal camera that scans many wavelengths of light can detect signs of Alzheimer’s and other neurodegenerative diseases in people with dementia or at risk.

  Recruiting Center for Eye Research Australia · Melbourne, Victoria · NCT07545473

• Collecting data on neurodegenerative diseases progression markers

  This study is trying to find new signs that can help doctors understand how neurodegenerative diseases like Parkinson's progress, so they can improve early treatment options for patients.

  Recruiting IRCCS San Raffaele Roma · Cassino, Frosinone · NCT06596746

• Effects of speech-language intervention on bilingual speakers with primary progressive aphasia

  This study tests if special speech therapy designed for bilingual people can help those with primary progressive aphasia communicate better in both of their languages.

  Recruiting at 2 sites University of Texas at Austin · Austin, Texas and 2 other locations · NCT05741853

• Cohort study on Alzheimer's risk in first-degree relatives

  This study looks at how likely first-degree relatives of Alzheimer's patients are to develop the disease themselves and what factors might affect that risk.

  Recruiting Ruijin Hospital · Shanghai, Shanghai Municipality · NCT05597410

• Using a passive home sensor to find digital signs of brain energy changes from nicotinamide riboside

  This project will try a contact-free home sensor to see if it can detect activity, sleep, and breathing changes related to nicotinamide riboside in people with mild cognitive impairment or mild Alzheimer's.

  Recruiting Mclean Hospital · Belmont, Massachusetts · NCT05245903

• Treatment for neurologic disorders using stem cells

  This study is testing whether using stem cells from patients' own bone marrow can help improve brain and nerve function in people with serious neurologic disorders that don't respond well to regular treatments.

  Recruiting at 3 sites MD Stem Cells · Westport, Connecticut and 2 other locations · NCT02795052

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.