Collecting cerebrospinal fluid to find new biomarkers for Alzheimer's disease
New Diagnosis or Prognosis Biomarkers for Alzheimer's Disease: Biobank of CSF Collected as Part of Differential Diagnosis of Dementia
This study is collecting spinal fluid from people getting tested for dementia to see if it can help find new ways to diagnose and treat Alzheimer's disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50000 (estimated) |
| Sex | All |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Nancy, Grand Est) |
| Trial ID | NCT03621839 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect cerebrospinal fluid samples from patients undergoing lumbar puncture as part of their dementia diagnosis. The goal is to identify and validate new biomarkers that could improve the diagnosis, prognosis, and treatment monitoring of Alzheimer's disease and other neurodegenerative conditions. By analyzing these samples, researchers hope to enhance the understanding of Alzheimer's pathology and develop more effective diagnostic tools.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals undergoing lumbar puncture for dementia diagnosis.
Not a fit: Patients who do not require a lumbar puncture for their dementia diagnosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and earlier diagnosis of Alzheimer's disease, improving patient management and outcomes.
How similar studies have performed: Other studies have explored biomarkers in Alzheimer's disease, but this specific approach to collecting and validating new biomarkers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Lumbar punction collected in usual practice in the context of dementia diagnosis Exclusion Criteria: * Absence of consent
Where this trial is running
Nancy, Grand Est
- CHRU De Nancy — Nancy, Grand Est, France (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.