Collecting blood samples to study metabolites in prostate cancer patients
Metabolic Profiling of Peripheral Blood Mononuclear Cells (PBMCs) by LC-MS in Prostate Cancer Patients
This study is collecting blood samples from prostate cancer patients to see if the small molecules in their blood can help us understand their disease better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | University of Southern California Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT03485794 on ClinicalTrials.gov |
What this trial studies
This observational pilot research focuses on collecting blood samples from patients with prostate cancer to study metabolites, which are small molecules produced during cellular metabolism. The study aims to develop reliable procedures for metabolomic profiling of peripheral blood mononuclear cells using advanced mass spectrometry techniques. It will also optimize data analysis methods to create metabolic profiles at the time of blood collection and compare these profiles across different blood fractions. The ultimate goal is to identify correlations between metabolite profiles and the disease state of patients.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with histologically confirmed prostate cancer who are willing to comply with the study procedures.
Not a fit: Patients with active infections or those who do not meet the inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and treatment strategies for prostate cancer patients.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in metabolomic profiling for other conditions, suggesting potential for success in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All subjects will have histologically confirmed prostate cancer * Provide written consent/authorization to participate in this study * Have no signs or symptoms of active infection * Exhibit a willingness to comply with the experimental procedures as outlined in this protocol
Where this trial is running
Los Angeles, California
- USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Jonathan Katz, Ph.D. — University of Southern California
- Study coordinator: Brandi Scott
- Email: Brandi.Scott@med.usc.edu
- Phone: 310-272-7653
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.