Clinical trial Recruiting at 1 site Observational Ages 18 and up

Collecting blood samples from patients treated with CAR-T cells for blood cancers

Official title: Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies in Montpellier University Hospital

Run by University Hospital, Montpellier · NCT04290000 · Data updated 2026-11-12

This study is collecting blood samples from patients with lymphoma and Acute Lymphoblastic Leukemia who have been treated with CAR-T cells to see what factors affect how well the treatment works.

More Acute Lymphoblastic Leukemia trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorUniversity Hospital, Montpellier
Academic / other
Drugs / interventionsCAR-T
Locations1 site (Montpellier)
StatusRecruiting
StartedMarch 27, 2020
Main results expectedSeptember 27, 2025
Study endsMarch 27, 2040
Registry record updatedJune 22, 2026
Trial IDNCT04290000 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have been treated with CAR-T cells at the University Hospital of Montpellier.

Probably not a fit

Patients who may not benefit from this study include those who refuse to sign the consent form or are pregnant.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect and bank blood samples from patients treated with CAR-T cells for hematological malignancies, specifically lymphoma and Acute Lymphoblastic Leukemia, at the University Hospital of Montpellier. The study will gather clinical data alongside the biological samples to investigate the factors influencing the efficacy of CAR-T cell treatments. By understanding the reasons behind treatment failures, the research seeks to optimize CAR-T cell therapies for better patient outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved CAR-T cell therapies and better treatment responses for patients with hematological malignancies.

How similar studies have gone: While CAR-T cell therapies have shown impressive outcomes in some studies, this specific approach to understanding treatment failures is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patient treated by CAR-T cell at the University Hospital of Montpellier

Exclusion Criteria:

* refusal to sign consent form
* pregnant woman
* major protected

Where it's running

  • Département d'hématologie clinique
    Montpellier, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.