Collaborative VR versus screen-based VR for Parkinson's rehabilitation
Official title: COMPARATIVE EFFECTIVENESS of COLLABORATIVE VIRTUAL ENVIRONMENT and NON-IMMERSIVE VIRTUAL REALITY in the REHABILITATION of PATIENTS With PARKINSON'S DISEASE
Run by Superior University · NCT07523425 · Data updated 2026-11-12
This study tries two types of virtual-reality rehabilitation—therapist-guided collaborative VR versus screen-based non-immersive VR—for people with mild to moderate Parkinson's to see which improves movement, thinking, and quality of life over 12 weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Superior University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | May 27, 2025 |
| Main results expected | September 27, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | April 15, 2026 |
| Trial ID | NCT07523425 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 45–80 with idiopathic Parkinson's disease at Hoehn & Yahr stages I–III, on stable medication, with preserved cognition (MMSE ≥ 24), and able to take part in in-person virtual-rehabilitation sessions.
✕Probably not a fit
Patients with severe cognitive impairment, major visual/hearing/motor deficits unrelated to Parkinson's, epilepsy or other VR contraindications, severe musculoskeletal limitations, advanced comorbidities, or an inability/unwillingness to attend in-person sessions are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will assign people with mild to moderate Parkinson's disease to either a therapist-guided Collaborative Virtual Environment (CVE) or a non-immersive, screen-based virtual-reality (NIVR) program. Both groups will complete task-oriented, goal-directed exercises targeting motor and cognitive function across a 12-week intervention with graded progression and performance-based adjustments. Primary outcomes focus on standardized motor function scales, while secondary outcomes measure cognition, mobility, and quality of life. Sessions are delivered in-person at Punjab Institute of Neurosciences in Lahore, with eligibility limited to patients on stable medication and without severe cognitive or sensory impairments.
Why it matters
Potential benefit: If successful, the collaborative VR approach could produce greater improvements in motor control, engagement, and daily functioning than standard screen-based VR for people with mild to moderate Parkinson's.
How similar studies have gone: Prior studies of screen-based and immersive VR have shown benefits for motor and functional outcomes in Parkinson's, but therapist-guided collaborative VR is less well-studied and represents a relatively novel comparison.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and Female * Age: 45 years-80 Years * Diagnosed patients of idiopathic Parkinson Disease with minor to moderate severity according to the Hoehn \& Yahr stages I-III. * On conventional and stable medical treatment at present * No severe cognitive impairments (MMSE ≥ 24). * Ability to participate in virtual rehabilitation sessions * Willingness to participate and provide informed consent Exclusion Criteria: * Severe visual, auditory, or motor impairments unrelated to Parkinson's. * Fear of virtual environment. * Comorbidities that hinder participation in the treatment (e.g., advanced dementia). * Severe musculoskeletal conditions limiting movement * History of epilepsy or conditions contraindicating virtual reality exposure * Participation in another interventional study within the last 3 months
Where it's running
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Punjab Institute of Neurosciences Lahore
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Hafiz Muddassir Riaz
- Email: muddassir.riaz@gmail.com
- Phone: +923456627409
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.