Cold snare polypectomy for duodenal adenomas in patients with Familial Adenomatous Polyposis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather prospective data on patients diagnosed with Familial Adenomatous Polyposis (FAP) who are undergoing cold snare polypectomy for duodenal adenomas. FAP is a genetic condition that leads to the development of numerous colorectal polyps and increases the risk of colorectal cancer. The study will focus on the effectiveness of cold snare polypectomy as a management strategy for duodenal adenomas, which are common in FAP patients. Data collected will help inform future treatment approaches and surveillance strategies for this high-risk population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient's diagnosed with a confirmed diagnosis of FAP (genetic testing) and able to give informed consent to involvement in trial. For patients who do not speak English, an interpreter will be asked to translate the informed consent
* Patients already commenced on endoscopic surveillance for FAP.

Exclusion Criteria:

* Patient's with known strictures/stenosis
* Pregnancy
* Patients who did not consent to study
* Bleeding diathesis

Where it's running

• Westmead Endoscopy Unit
  Westmead, New South Wales, Australia Recruiting

Study contacts

• Study coordinator: Michael J Bourke, MBBS
• Email: michael@citywestgastro.com.au
• Phone: 88905555

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Classifying duodenal polyps in familial adenomatous polyposis

  This project will test two risk models to see if they better predict dangerous duodenal polyps and cancer risk in people with genetically confirmed FAP.

  Recruiting at 2 sites Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Milan, MI and 1 other locations · NCT07199127

• Personalized home treadmill exercise for people with Familial Adenomatous Polyposis (FAP)

  This trial will try different amounts of home treadmill exercise in people with FAP who have at least five rectal polyps to see if exercise can help prevent polyps from coming back.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan and 1 other locations · NCT06641310

• Investigating factors that influence polyp development in patients with Familial Adenomatous Polyposis

  This study looks at how gut bacteria and environmental factors might affect polyp growth in people with Familial Adenomatous Polyposis who have had preventive surgery and regular check-ups.

  Recruiting at 2 sites Hospices Civils de Lyon · Lyon, France and 1 other locations · NCT06614738

• TPST-1495 treatment for people with familial adenomatous polyposis

  This trial will try an oral drug called TPST-1495 to see if it reduces the number of polyps in the small bowel and colon in people with familial adenomatous polyposis.

  Recruiting at 2 sites Phase 2 National Cancer Institute (NCI) · Phoenix, Arizona and 3 other locations · NCT06557733

• 10 cm versus 15 cm J-shaped ileal pouch after IPAA surgery

  This trial will see if a 10 cm or a 15 cm J-pouch gives better bowel function and quality of life for people having IPAA for ulcerative colitis or familial adenomatous polyposis.

  Recruiting at 2 sites Odense University Hospital · Aarhus and 1 other locations · NCT06538402

• ONC201 (dordaviprone) for safety and prevention of colorectal polyps in high-risk adults.

  This trial tests whether different doses of ONC201 (dordaviprone) are safe and can help prevent new colorectal polyps in adults with familial adenomatous polyposis or a history of multiple adenomas.

  Recruiting at 3 sites Phase 1 National Cancer Institute (NCI) · Ann Arbor, Michigan and 4 other locations · NCT05630794

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.