Cold snare polypectomy for duodenal adenomas in patients with Familial Adenomatous Polyposis
Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
This study is testing whether a method called cold snare polypectomy is effective for removing duodenal adenomas in patients with Familial Adenomatous Polyposis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Western Sydney Local Health District Academic / other |
| Locations | 1 site (Westmead, New South Wales) |
| Trial ID | NCT03471403 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather prospective data on patients diagnosed with Familial Adenomatous Polyposis (FAP) who are undergoing cold snare polypectomy for duodenal adenomas. FAP is a genetic condition that leads to the development of numerous colorectal polyps and increases the risk of colorectal cancer. The study will focus on the effectiveness of cold snare polypectomy as a management strategy for duodenal adenomas, which are common in FAP patients. Data collected will help inform future treatment approaches and surveillance strategies for this high-risk population.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with a confirmed diagnosis of Familial Adenomatous Polyposis who are already undergoing endoscopic surveillance.
Not a fit: Patients with known strictures or stenosis, those who are pregnant, or those who do not consent to participate may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management of duodenal adenomas in patients with FAP, potentially reducing the risk of cancer development.
How similar studies have performed: While there have been studies on endoscopic management of duodenal adenomas, the specific approach of cold snare polypectomy in this context is less commonly explored, making this study somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient's diagnosed with a confirmed diagnosis of FAP (genetic testing) and able to give informed consent to involvement in trial. For patients who do not speak English, an interpreter will be asked to translate the informed consent * Patients already commenced on endoscopic surveillance for FAP. Exclusion Criteria: * Patient's with known strictures/stenosis * Pregnancy * Patients who did not consent to study * Bleeding diathesis
Where this trial is running
Westmead, New South Wales
- Westmead Endoscopy Unit — Westmead, New South Wales, Australia (Recruiting)
Study contacts
- Study coordinator: Michael J Bourke, MBBS
- Email: michael@citywestgastro.com.au
- Phone: 88905555
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.