Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Cohort study on testicular cancer follow-up strategies

Official title: Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS

Run by Cantonal Hospital of St. Gallen · NCT02229916 · Data updated 2026-11-12

This study looks at different ways to check for any return of testicular cancer in patients who are in complete remission to see which methods work best for their follow-up care.

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Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment6900 (estimated)
SponsorCantonal Hospital of St. Gallen
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Sankt Gallen)
StatusRecruiting
StartedDecember 2013
Main results expectedDecember 2028
Study endsDecember 2033
Registry record updatedJanuary 13, 2026
Trial IDNCT02229916 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include young men with histologically proven seminomas or non-seminomas who have recently completed treatment and are in complete remission.

Probably not a fit

Patients with co-existing malignancies or those unable to comply with follow-up schedules may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of various diagnostic tests and follow-up strategies for patients with testicular cancer who have achieved complete remission. It focuses on the early detection of relapses using methods such as radiographs, CT scans, and serum tumor markers, while also assessing the patterns of care and long-term outcomes for these patients. The study seeks to standardize follow-up procedures to improve patient care and minimize unnecessary interventions. By collecting data on treatment sequelae and patient characteristics, the study aims to enhance understanding of the disease's impact on survivors.

Why it matters

Potential benefit: If successful, this study could lead to improved follow-up protocols that enhance early relapse detection and reduce unnecessary treatments for testicular cancer survivors.

How similar studies have gone: Other studies have shown success in improving follow-up strategies for testicular cancer, making this approach both relevant and necessary.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written informed consent.
* Histologically proven seminomas or non-seminoma.
* Seminoma: complete remission (CR) or lymph nodes (LN) \< 3cm or PET negative partial remission (PR) or non-seminoma: CR.
* Completion of treatment within the last 6 months.
* Patient able and willing to attend for regular surveillance.

Exclusion Criteria:

* Co-existent malignancy within 5 years.
* Inability for any reason to comply with the trial investigations or follow-up schedules.

Where it's running

  • Kantonsspital St.Gallen; Onkologie/Haematologie
    Sankt Gallen, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Christian Rothermundt, Dr. med. — Cantonal Hospital of St. Gallen

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.