Cohort of patients with ST-segment elevation myocardial infarction
CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in ST Elevation Myocardial Infarction
This study is looking at patients with a serious heart condition called STEMI to see how it affects their health and quality of life, while also collecting data to help improve future treatments.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 2 sites (Bron, Rhone and 1 other locations) |
| Trial ID | NCT05794022 on ClinicalTrials.gov |
What this trial studies
This cohort focuses on patients diagnosed with ST-segment elevation myocardial infarction (STEMI), a critical condition that significantly contributes to sudden deaths and chronic heart failure. The study aims to collect data on the epidemiology of myocardial infarction, monitor treatment outcomes, assess quality of life, and explore new biological and imaging biomarkers. By utilizing MRI and biocollection methods, the cohort will provide valuable insights for researchers and healthcare professionals. The overarching goal is to create a comprehensive epidemiological tool for future research and clinical applications.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who have been diagnosed with STEMI and are undergoing primary treatment.
Not a fit: Patients with unconfirmed STEMI diagnosis or those with contraindications to MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of myocardial infarction and improve patient management and outcomes.
How similar studies have performed: While there is limited information on similar cohort studies specifically for STEMI, the approach of utilizing biocollection and imaging biomarkers has shown promise in other cardiovascular research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of STEMI defined by ST segment elevation ≥ 0.2 mV in 2 contiguous leads on a 12-lead ECG. * Management in primary ACT * Prior oral informed consent followed by signed informed consent as soon as possible. Exclusion Criteria: * Diagnosis of STEMI not confirmed on angiography * Inability to give the subject informed information * Lack of coverage by a social security scheme * Obvious contraindication to injected magnetic resonance imaging (claustrophobia, pacemaker, defibrillator, or a metallic body (ferromagnetic), severe renal insufficiency (GFR\<30 ml/min), known allergy to the contrast medium ....) * Pregnant woman or woman of childbearing age without effective contraception, breastfeeding woman. * Deprivation of civil rights (curators, guardianship, safeguard of justice)
Where this trial is running
Bron, Rhone and 1 other locations
- Hospices Civils de Lyon - Hôpital Louis Pradel — Bron, Rhone, France (Recruiting)
- Hospices Civils de Lyon - Hôpital de la Croix Rousse — Lyon, Rhone, France (Recruiting)
Study contacts
- Study coordinator: Thomas BOCHATON, Dr
- Email: thomas.bochaton@chu-lyon.fr
- Phone: 04 72 35 75 41
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.