Cognitive screening for lung cancer patients
Official title: Cognitive Screening in Lung Cancer Patients
Run by European Institute of Oncology · NCT06727370 · Data updated 2026-11-12
This study is trying to see if lung cancer and its treatments affect thinking skills in patients during their first year after diagnosis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | European Institute of Oncology Academic / other |
| Locations | 1 site (Milan) |
| Status | Recruiting |
| Started | January 10, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | December 10, 2024 |
| Trial ID | NCT06727370 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older diagnosed with stage I to IV NSCLC or SCLC who can provide informed consent.
✕Probably not a fit
Patients aged 70 and older, those with brain metastases, or those with neurological or psychiatric disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates cognitive impairment related to cancer and its treatment in patients with non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). It aims to assess the presence of cognitive deficits during the first year after enrollment using comprehensive neuropsychological assessments. The study focuses on understanding how lung cancer and its therapies may affect cognitive function over time.
Why it matters
Potential benefit: If successful, this study could lead to better management strategies for cognitive impairment in lung cancer patients.
How similar studies have gone: While cognitive impairment in cancer patients has been studied, this specific focus on lung cancer and its treatments is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Small-cell and non-small-cell lung cancer (stage I, II, III, IV) * Age ≥ 18 years * Patients able to speak and read the local language(s) fluently * Acceptance and signature of informed consent Exclusion Criteria: * Age ≥ 70 * Presence of brain metastases * Patients with concomitant neurological or psychiatric disorders. * Patients undergoing brain radiotherapy * Previous diagnosis of lung cancer
Where it's running
-
Istituto Europeo di Oncologia
Milan, Italy Recruiting
Study contacts
- Principal investigator: Gabriella Pravettoni — Istituto Europeo di Oncologia
- Study coordinator: Gabriella Pravettoni
- Email: gabriella.pravettoni@ieo.it
- Phone: +39025489731
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Investigating KQB365 for treating advanced solid tumors
This study tests if a new treatment called KQB365, alone or with another drug, can help adults with advanced solid tumors that have specific genetic mutations.
-
Evaluating PC14586 for advanced solid tumors with a specific mutation
This study is testing a new oral medication called PC14586 to see if it can help people with advanced solid tumors that have a specific mutation in the TP53 gene.
-
TS-104: a first-in-human, dose-escalation study for advanced solid tumors
This study tests TS-104, a peptide-drug conjugate, as a single therapy in adults with advanced solid tumors like NSCLC, HNSCC, esophageal, gastric, ovarian, or endometrial cancer to see if it is safe and tolerable and whether it shows any benefit.
-
Icotinib after surgery for early EGFR-mutant NSCLC
This study tests whether giving icotinib after surgery helps patients with early-stage EGFR-mutant NSCLC compare to just following them after surgery.
-
Oral Paclitaxel with Immunotherapy and SBRT as Neoadjuvant Treatment for Older Adults with NSCLC
This trial tests a new, lighter neoadjuvant therapy that combines an oral paclitaxel solution, an immune checkpoint inhibitor, and SBRT for adults aged 70 and older with resectable NSCLC to see if it can shrink tumors before surgery.
-
Targeted Induction Therapy for Stage III Unresectable EGFR Mutant NSCLC
This trial tests a targeted induction approach using fumetinib with platinum-based chemotherapy and concurrent radiochemotherapy in adults with unresectable stage III EGFR-mutant NSCLC to see if this combo can improve outcomes before possible surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.