Cognitive-psychophysiological therapy, with or without biofeedback, for tics in young people with Tourette's

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants complete two pre-treatment interviews totaling about six hours that measure tic severity (including the YGTSS), psychosocial, neurocognitive, and biological variables, plus general intelligence and executive function. They then receive 10 to 12 sessions of cognitive-psychophysiological therapy either with or without a biofeedback component. Outcomes include tic severity and Clinical Global Impression scores, measured through the planned follow-up visits. The protocol is delivered in French at a Montreal clinical site, with project explanations available in English.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Have a diagnosis of TS or to experience bothersome tics;
* Be aged 14 to 21 years inclusive at the start of therapy.

Exclusion Criteria:

* Present a sensorimotor impairment;
* Have a diagnosis of intellectual disability (intelligence quotient below 75);
* Alcohol or drug abuse;
* A neurological issue (e.g., hemifacial spasms, Huntington's disease);
* Change medication one month or less before step 1 and up to step 4 (last measurement time) without informing a member of the research team;
* Simultaneously receive another intervention for tics (e.g., psychologist, massage therapist) without informing a research team member.

Where it's running

• Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal, Hôpital Rivières-des-Prairies
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Julie Leclerc, Psychology — Université du Québec à Montréal- UQAM
• Study coordinator: Julie Leclerc, Psychology
• Email: leclerc.julie@uqam.ca
• Phone: 1-514-987-3000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.